Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 11/20 | 0.59 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL10796044 | 0.80 | TGM2 (0.52) | TGM2ITGB3ITGA2B | |
| SCHEMBL1091976 | 0.80 | TGM2 (0.71) | TGM2 | |
| SCHEMBL1091980 | 0.80 | TGM2 (0.71) | TGM2 | |
| SCHEMBL1091978 | 0.80 | TGM2 (0.71) | TGM2 | |
| SCHEMBL4935926 | 0.79 | TGM2 (0.72) | TGM2 | |
| SCHEMBL9827028 | 0.78 | TGM2 (0.69) | TGM2 | |
| SCHEMBL4657328 | 0.78 | TGM2 (0.58) | TGM2ITGB3ITGA2B | |
| SCHEMBL1091157 | 0.78 | TGM2 (0.93) | TGM2 | |
| SCHEMBL1091124 | 0.78 | TGM2 (0.93) | TGM2 | |
| SCHEMBL1091158 | 0.78 | TGM2 (0.93) | TGM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0237082-B1 | 3,5-DISUBSTITUTED 4,5-DIHYDROISOXAZOLES AS TRANSGLUTAMINASE INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1991-05-29 | — | — | EP | disclosed |
| US-4929630-A | SKIN DISORDERS, ACNE, 4,5-DIHYDROISOOXAZOLE PEPTIDES | SYNTEX (U.S.A.) INC. (US) | 1990-05-29 | — | — | US | disclosed |
| US-4912120-A | Containing amine and amide substitution | SYNTEX (U.S.A.) INC. (US) | 1990-03-27 | — | — | US | disclosed |