Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 3/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 6/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9828644 | 0.84 | HTR1A (0.41) | HTR1AHTR6 | |
| SCHEMBL9827759 | 0.80 | HTR1A (0.41) | HTR1AHTR6 | |
| SCHEMBL9828705 | 0.80 | HTR1A (0.41) | HTR1ASLC6A2SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL9828460 | 0.79 | HTR1A (0.42) | HTR1AHTR6 | |
| SCHEMBL9828411 | 0.71 | HTR1A (0.42) | HTR1A | |
| SCHEMBL7376163 | 0.70 | HTR1A (0.73) | HTR1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL10658365 | 0.68 | CES1 (0.51) | HTR1A | |
| SCHEMBL9827478 | 0.66 | CES1 (0.42) | HTR1AHTR6 | |
| SCHEMBL9830196 | 0.64 | MAP2K1 (0.41) | HTR1AHTR6 | |
| SCHEMBL11719507 | 0.63 | HTR1A (0.40) | HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0239129-B1 | HYDROQUINOLINE COMPOUNDS, COMPOSITIONS CONTAINING SAME AND PROCESSES FOR PREPARING SAME | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-09-25 | — | — | EP | disclosed |
| US-4963566-A | ANTIULCER AGENT | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1990-10-16 | — | — | US | disclosed |
| EP-0239129-A2 | Hydroquinoline compounds, compositions containing same and processes for preparing same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1987-09-30 | — | — | EP | disclosed |