Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.62 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.40 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6971203 | 0.88 | CYP4F2 (0.78) | CYP4F2CYP4A11TSHRMAPTRAB9A | |
| SCHEMBL9828113 | 0.84 | CYP4F2 (0.51) | CYP4F2CYP4A11TSHRALDH1A1HSD17B10 | |
| SCHEMBL10003354 | 0.78 | CYP4F2 (0.60) | CYP4F2CYP4A11TSHRALDH1A1HSD17B10 | |
| SCHEMBL27318143 | 0.78 | CYP4F2 (0.61) | CYP4F2CYP4A11TSHRMAPTRAB9A | |
| SCHEMBL22098189 | 0.77 | CYP4F2 (1.00) | CYP4F2CYP4A11TSHRALDH1A1HPGD | |
| SCHEMBL522636 | 0.76 | CYP4F2 (0.57) | CYP4F2CYP4A11TSHRMAPTRAB9A | |
| SCHEMBL22684772 | 0.75 | CYP4F2 (0.46) | CYP4F2CYP4A11TSHRTP53ALDH1A1 | |
| SCHEMBL20077738 | 0.74 | SMN1; SMN2 (0.57) | CYP4F2CYP4A11TSHRMAPTRAB9A | |
| SCHEMBL7119653 | 0.74 | CYP4F2 (0.68) | CYP4F2CYP4A11TSHRALDH1A1HSD17B10 | |
| SCHEMBL7410301 | 0.74 | CYP4F2 (0.68) | CYP4F2CYP4A11TSHRALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0150892-B1 | SUBSTITUTED ALKYLIDENE IMIDAZOLES | G.D. Searle & Co. (US) | 1991-04-24 | — | — | EP | disclosed |
| US-4837333-A | SELECTIVE INHIBITOR OF THROMBOXANE SYNTHETASE ENZYME | G. D. SEARLE & CO. (US) | 1989-06-06 | — | — | US | disclosed |
| EP-0150892-A2 | Substituted alkylidene imidazoles | G.D. Searle & Co. (US) | 1985-08-07 | — | — | EP | disclosed |