Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GALR3 | O60755 | 1/20 | 0.40 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.40 |
| ▸ | GPR183 | P32249 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.33 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11938602 | 0.88 | SMN1; SMN2 (0.46) | SMN1; SMN2LMNANPC1RAB9AMEN1 | |
| SCHEMBL10565137 | 0.87 | SMN1; SMN2 (0.44) | SMN1; SMN2LMNANPC1RAB9AMEN1 | |
| SCHEMBL21511186 | 0.87 | SMN1; SMN2 (0.47) | SMN1; SMN2LMNANPC1RAB9AMEN1 | |
| SCHEMBL16901904 | 0.85 | SMN1; SMN2 (0.43) | SMN1; SMN2LMNANPC1RAB9AMEN1 | |
| SCHEMBL12722376 | 0.84 | SMN1; SMN2 (0.47) | SMN1; SMN2LMNANPC1RAB9AMEN1 | |
| SCHEMBL16901896 | 0.84 | SMN1; SMN2 (0.43) | SMN1; SMN2LMNANPC1RAB9AMEN1 | |
| SCHEMBL18672266 | 0.83 | SMN1; SMN2 (0.53) | SMN1; SMN2LMNANPC1RAB9AMEN1 | |
| SCHEMBL9829249 | 0.83 | SMN1; SMN2 (0.41) | SMN1; SMN2LMNANPC1RAB9AMEN1 | |
| SCHEMBL16901911 | 0.82 | SMN1; SMN2 (0.45) | SMN1; SMN2LMNANPC1RAB9AMEN1 | |
| SCHEMBL9827494 | 0.82 | SMN1; SMN2 (0.45) | SMN1; SMN2LMNANPC1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0199281-B1 | PYRIDAZINONE DERIVATIVES, PREPARATION THEREOF, AND INSECTICIDAL, ACARICIDAL, NEMATICIDAL, FUNGICIDAL COMPOSITIONS | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1991-07-10 | — | — | EP | disclosed |
| US-4837217-A | Pyridazinone derivatives, preparation thereof, and insecticidal, acaricidal, nematicidal, fungicidal compositions | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1989-06-06 | — | — | US | disclosed |
| EP-0199281-A2 | Pyridazinone derivatives, preparation thereof, and insecticidal, acaricidal, nematicidal, fungicidal compositions | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1986-10-29 | — | — | EP | disclosed |