Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | GALR3 | O60755 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2562191 | 0.74 | TSHR (0.38) | TSHRTDP1CHRM2CHRM4CHRM1 | |
| SCHEMBL2254844 | 0.74 | — | — | |
| SCHEMBL10422950 | 0.72 | TSHR (0.44) | TSHRTDP1CHRM2CHRM4CHRM1 | |
| SCHEMBL8706061 | 0.72 | ALDH1A1 (0.53) | TSHRTDP1MEN1KMT2AMAPT | |
| SCHEMBL16075606 | 0.72 | TSHR (0.55) | TSHRTDP1CHRM2CHRM4CHRM1 | |
| SCHEMBL7785079 | 0.68 | — | — | |
| SCHEMBL7785077 | 0.68 | — | — | |
| SCHEMBL14963619 | 0.66 | ALDH1A1 (0.46) | TSHRTDP1CHRM2CHRM4CHRM1 | |
| SCHEMBL9019766 | 0.66 | TSHR (0.36) | TSHRTDP1CHRM2CHRM4CHRM1 | |
| SCHEMBL14478574 | 0.66 | TDP1 (0.56) | TSHRTDP1CHRM2CHRM4CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0217207-B1 | 2-AMINO PURINES SUBSTITUTED IN POSITIONS 6 AND 9, THEIR USE, MEDICAMENTS CONTAINING THESE PURINES AND PROCESSES FOR THEIR PREPARATION | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-04-10 | — | — | EP | disclosed |