Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 9/20 | 0.50 |
| ▸ | CA12 | O43570 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
| ▸ | GLA | P06280 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | F2 | P00734 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | IMPDH2 | P12268 | 2/20 | 0.47 |
| ▸ | FLT3 | P36888 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9826855 | 0.95 | CA12 (0.49) | CYP3A4CA12CA9GLAALDH1A1 | |
| SCHEMBL6958458 | 0.88 | CYP3A4 (0.49) | CYP3A4TDP1IMPDH2CYP1A2CYP2C19 | |
| SCHEMBL8414749 | 0.83 | CYP3A4 (0.51) | CYP3A4IMPDH2ROCK2 | |
| SCHEMBL3974361 | 0.83 | CA12 (0.65) | CYP3A4CA12CA9GLAALDH1A1 | |
| SCHEMBL30595409 | 0.83 | CA12 (0.65) | CYP3A4CA12CA9GLAALDH1A1 | |
| SCHEMBL14418569 | 0.82 | CA12 (0.53) | CYP3A4CA12CA9GLAALDH1A1 | |
| SCHEMBL19641879 | 0.81 | CYP3A4 (0.49) | CYP3A4IMPDH2CYP1A2CYP2C19 | |
| SCHEMBL9623200 | 0.81 | IKBKB (0.47) | CYP3A4CA12CA9GLAALDH1A1 | |
| 4-Acetoxyphenol SCHEMBL28093126 | 0.80 | KMT2A (0.46) | CYP3A4ALDH1A1KDM4EPOLBGAA | |
| SCHEMBL29705954 | 0.79 | CA12 (0.61) | CYP3A4CA12CA9GLAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0182210-A2 | Cephalosporin derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1986-05-28 | — | — | EP | claimed |
| EP-0182210-B1 | CEPHALOSPORIN DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1991-02-27 | — | — | EP | disclosed |
| US-4742053-A | ANTIBIOTICS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1988-05-03 | — | — | US | disclosed |
| EP-0182210-A2 | Cephalosporin derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1986-05-28 | — | — | EP | disclosed |