Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD1 | Q9Y239 | 7/20 | 0.70 |
| ▸ | FAAH | O00519 | 7/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.55 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.51 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8511271 | 0.98 | NOD1 (0.73) | NOD1FAAHMEN1MAPK1KMT2A | |
| SCHEMBL14438857 | 0.98 | NOD1 (0.73) | NOD1FAAHMEN1MAPK1KMT2A | |
| SCHEMBL13965865 | 0.98 | NOD1 (0.73) | NOD1FAAHMEN1MAPK1KMT2A | |
| SCHEMBL9830495 | 0.98 | NOD1 (0.73) | NOD1FAAHMEN1MAPK1KMT2A | |
| SCHEMBL20225680 | 0.98 | NOD1 (0.73) | NOD1FAAHMEN1MAPK1KMT2A | |
| SCHEMBL31422291 | 0.98 | NOD1 (0.73) | NOD1FAAHMEN1MAPK1KMT2A | |
| SCHEMBL31422440 | 0.98 | NOD1 (0.73) | NOD1FAAHMEN1MAPK1KMT2A | |
| SCHEMBL22262078 | 0.98 | NOD1 (0.73) | NOD1FAAHMEN1MAPK1KMT2A | |
| SCHEMBL4627107 | 0.94 | NOD1 (0.62) | NOD1FAAHMEN1MAPK1KMT2A | |
| SCHEMBL15623817 | 0.94 | NOD1 (0.61) | NOD1FAAHMEN1MAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0226304-B1 | COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC | SANKYO COMPANY LIMITED (JP) | 1991-08-28 | — | — | EP | disclosed |
| US-4757066-A | Reduces renal toxicity | SANKYO COMPANY LIMITED (JP) | 1988-07-12 | — | — | US | disclosed |
| EP-0226304-A1 | Composition containing a penem or carbapenem antibiotic | SANKYO COMPANY LIMITED (JP) | 1987-06-24 | — | — | EP | disclosed |