Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 10/20 | 0.50 |
| ▸ | PARP15 | Q460N3 | 9/20 | 0.50 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.50 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.46 |
| ▸ | HTR3A | P46098 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10267513 | 0.91 | PARP10 (0.54) | PARP10PARP15 | |
| SCHEMBL20982652 | 0.87 | PARP10 (0.41) | PARP10PARP15PARP2NR4A1SLC6A2 | |
| SCHEMBL20982651 | 0.87 | PARP10 (0.41) | PARP10PARP15PARP2NR4A1SLC6A2 | |
| SCHEMBL20982684 | 0.85 | MAOA (0.52) | KCNH2 | |
| SCHEMBL2566669 | 0.84 | PARP10 (0.55) | PARP10PARP15PARP2SLC6A2SLC6A4 | |
| SCHEMBL1850715 | 0.84 | PARP10 (0.46) | PARP10PARP15PARP2SLC6A2SLC6A4 | |
| SCHEMBL9227709 | 0.84 | PARP10 (0.51) | PARP10PARP15PARP2SLC6A2SLC6A4 | |
| SCHEMBL12432327 | 0.84 | PARP10 (0.46) | PARP10PARP15PARP2SLC6A2SLC6A4 | |
| SCHEMBL27037870 | 0.84 | PARP10 (0.50) | PARP10PARP15PARP2SLC6A2SLC6A4 | |
| SCHEMBL21694044 | 0.82 | PARP10 (0.42) | PARP10PARP15PARP2SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0240158-B1 | BENZIMIDAZOLE DERIVATIVES | TOKYO TANABE COMPANY LIMITED (JP) | 1991-04-03 | — | — | EP | disclosed |
| US-4753955-A | ANTIULCER | TOKYO TANABE COMPANY, LTD. (JP) | 1988-06-28 | — | — | US | disclosed |
| EP-0240158-A1 | Benzimidazole derivatives | TOKYO TANABE COMPANY LIMITED (JP) | 1987-10-07 | — | — | EP | disclosed |