Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 14/20 | 0.49 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 2/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9828306 | 0.92 | ACHE (0.50) | ACHECES2EPHX1 | |
| SCHEMBL10764218 | 0.92 | ACHE (0.50) | ACHECES2EPHX1 | |
| SCHEMBL9829993 | 0.89 | EPHX1 (0.53) | ACHEFAAHEPHX1 | |
| SCHEMBL9828366 | 0.85 | ACHE (0.61) | ACHECES2EPHX1 | |
| SCHEMBL9829745 | 0.85 | ACHE (0.61) | ACHECES2EPHX1 | |
| Bromide SCHEMBL9828440 | 0.83 | ACHE (0.46) | ACHECES2 | |
| SCHEMBL9828883 | 0.83 | EPHX1 (0.53) | ACHEFAAHEPHX1 | |
| SCHEMBL9828811 | 0.83 | EPHX1 (0.53) | ACHEFAAHEPHX1 | |
| SCHEMBL9828134 | 0.83 | EPHX1 (0.53) | ACHEFAAHEPHX1 | |
| SCHEMBL9828474 | 0.81 | ACHE (0.47) | ACHECES2EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0247201-B1 | PROPANE-1,3-DIOL DERIVATIVES, A METHOD FOR THEIR PRODUCTION AND A PHARMACEUTICAL COMPOSITION | LEO PHARMACEUTICAL PRODUCTS LTD. A/S (LOVENS KEMISKE FABRIK PRODUKTIONSAKTIESELSKAB) (DK) | 1991-05-15 | — | — | EP | disclosed |
| US-4945098-A | Novel propane-1,3-diol derivatives and use | LEO PHARMACEUTICAL PRODUCTS LTD. A/S (LOVENS KEMISKE FABRIK PRODUKTIONSAKTIESELSKAB) (DK) | 1990-07-31 | — | — | US | disclosed |
| EP-0247201-A1 | PROPANE-1,3-DIOL DERIVATIVES, A METHOD FOR THEIR PRODUCTION AND A PHARMACEUTICAL COMPOSITION. | LEO PHARM PROD LTD (DK) | 1987-12-02 | — | — | EP | disclosed |
| WO-1987003281-A1 | PROPANE-1,3-DIOL DERIVATIVES, A METHOD FOR THEIR PRODUCTION AND A PHARMACEUTICAL COMPOSITION | LEO PHARMACEUTICAL PRODUCTS LTD. A/S (DK) | 1987-06-04 | — | — | WO | disclosed |