Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | MME | P08473 | 8/20 | 0.47 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.42 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.39 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | APAF1 | O14727 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9828845 | 1.00 | HTT (0.57) | HTTMMESLC1A3GPR132TSHR | |
| SCHEMBL8602939 | 0.87 | MME (0.49) | HTTMMESLC1A3GPR132TSHR | |
| SCHEMBL4116995 | 0.81 | CTSK (0.51) | MME | |
| SCHEMBL3414715 | 0.81 | CTSK (0.51) | MME | |
| SCHEMBL3379781 | 0.81 | CTSK (0.51) | MME | |
| SCHEMBL14250689 | 0.81 | CTSK (0.51) | MME | |
| SCHEMBL844407 | 0.81 | CTSK (0.51) | MME | |
| SCHEMBL6121510 | 0.80 | HTT (0.60) | HTTTSHRGAASMN1; SMN2KMT2A | |
| SCHEMBL6435779 | 0.80 | HTT (0.60) | HTTTSHRGAASMN1; SMN2KMT2A | |
| SCHEMBL2329884 | 0.80 | MME (0.51) | MMEGAASMN1; SMN2KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0226304-B1 | COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC | SANKYO COMPANY LIMITED (JP) | 1991-08-28 | — | — | EP | disclosed |
| US-4757066-A | Reduces renal toxicity | SANKYO COMPANY LIMITED (JP) | 1988-07-12 | — | — | US | disclosed |
| EP-0226304-A1 | Composition containing a penem or carbapenem antibiotic | SANKYO COMPANY LIMITED (JP) | 1987-06-24 | — | — | EP | disclosed |