Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G1B | P04054 | 1/20 | 0.38 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 10/20 | 0.37 |
| ▸ | NPC1 | O15118 | 6/20 | 0.37 |
| ▸ | RAB9A | P51151 | 6/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | MITF | O75030 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | GALR3 | O60755 | 1/20 | 0.34 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.34 |
| ▸ | GPR183 | P32249 | 1/20 | 0.34 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 4/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9233774 | 0.81 | SMN1; SMN2 (0.50) | PLA2G1BATG4BSMN1; SMN2NPC1RAB9A | |
| SCHEMBL9237010 | 0.79 | SMN1; SMN2 (0.38) | PLA2G1BATG4BSMN1; SMN2NPC1RAB9A | |
| SCHEMBL9775182 | 0.78 | PLA2G1B (0.38) | PLA2G1BATG4BSMN1; SMN2NPC1RAB9A | |
| SCHEMBL1627207 | 0.78 | SMN1; SMN2 (0.46) | PLA2G1BATG4BSMN1; SMN2NPC1RAB9A | |
| SCHEMBL11274814 | 0.78 | PLA2G1B (0.38) | PLA2G1BATG4BSMN1; SMN2NPC1RAB9A | |
| SCHEMBL8281635 | 0.75 | MTOR (0.43) | SMN1; SMN2NPC1RAB9AALDH1A1MITF | |
| SCHEMBL8551357 | 0.70 | SMN1; SMN2 (0.37) | PLA2G1BATG4BSMN1; SMN2NPC1RAB9A | |
| SCHEMBL17191914 | 0.70 | SMN1; SMN2 (0.35) | PLA2G1BATG4BSMN1; SMN2NPC1RAB9A | |
| SCHEMBL23399663 | 0.70 | CYP17A1 (0.32) | CYP1A2 | |
| SCHEMBL10368396 | 0.70 | CNR1 (0.39) | PLA2G1BATG4BSMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0199281-B1 | PYRIDAZINONE DERIVATIVES, PREPARATION THEREOF, AND INSECTICIDAL, ACARICIDAL, NEMATICIDAL, FUNGICIDAL COMPOSITIONS | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1991-07-10 | — | — | EP | disclosed |
| US-4837217-A | Pyridazinone derivatives, preparation thereof, and insecticidal, acaricidal, nematicidal, fungicidal compositions | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1989-06-06 | — | — | US | disclosed |
| EP-0199281-A2 | Pyridazinone derivatives, preparation thereof, and insecticidal, acaricidal, nematicidal, fungicidal compositions | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1986-10-29 | — | — | EP | disclosed |