Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G1B | P04054 | 1/20 | 0.38 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 10/20 | 0.34 |
| ▸ | NPC1 | O15118 | 5/20 | 0.34 |
| ▸ | RAB9A | P51151 | 5/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | MITF | O75030 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | GALR3 | O60755 | 1/20 | 0.34 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.34 |
| ▸ | GPR183 | P32249 | 1/20 | 0.34 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 4/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9233774 | 0.81 | SMN1; SMN2 (0.50) | PLA2G1BATG4BSMN1; SMN2NPC1RAB9A | |
| SCHEMBL9235153 | 0.79 | SMN1; SMN2 (0.38) | PLA2G1BATG4BSMN1; SMN2NPC1RAB9A | |
| SCHEMBL11274814 | 0.78 | PLA2G1B (0.38) | PLA2G1BATG4BSMN1; SMN2NPC1RAB9A | |
| SCHEMBL9828853 | 0.78 | PLA2G1B (0.38) | PLA2G1BATG4BSMN1; SMN2NPC1RAB9A | |
| SCHEMBL3847199 | 0.78 | SMN1; SMN2 (0.46) | PLA2G1BATG4BSMN1; SMN2NPC1RAB9A | |
| SCHEMBL14012593 | 0.68 | TSHR (0.39) | PLA2G1BATG4BSMN1; SMN2NPC1RAB9A | |
| SCHEMBL12410744 | 0.67 | TSHR (0.41) | PLA2G1BATG4BSMN1; SMN2NPC1RAB9A | |
| SCHEMBL10368396 | 0.66 | CNR1 (0.39) | PLA2G1BATG4BSMN1; SMN2NPC1RAB9A | |
| SCHEMBL9096237 | 0.65 | SMN1; SMN2 (0.33) | SMN1; SMN2NPC1RAB9AALDH1A1KMT2A | |
| SCHEMBL1627210 | 0.65 | SMN1; SMN2 (0.50) | SMN1; SMN2NPC1RAB9AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0239728-A2 | Pyridazinone derivatives and the preparation thereof | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1987-10-07 | — | — | EP | claimed |
| EP-0134439-A1 | Pyridazinone derivatives, preparation thereof and insecticidal, acaricidal, fungicidal compositions | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1985-03-20 | — | — | EP | claimed |
| US-5026850-A | Pyridazinone derivatives, preparation thereof, and insecticidal, acaricidal, fungicidal compositions | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1991-06-25 | — | — | US | disclosed |
| US-4877787-A | Benzylthio pyridazinone derivatives, preparation thereof, and insecticidal acaricidal, fungicidal compositions | NISSAN CHEMICAL INDUSTRIES (JP) | 1989-10-31 | — | — | US | disclosed |
| EP-0134439-B1 | PYRIDAZINONE DERIVATIVES, PREPARATION THEREOF AND INSECTICIDAL, ACARICIDAL, FUNGICIDAL COMPOSITIONS | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1988-08-24 | — | — | EP | disclosed |
| EP-0239728-A2 | Pyridazinone derivatives and the preparation thereof | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1987-10-07 | — | — | EP | disclosed |
| EP-0134439-A1 | Pyridazinone derivatives, preparation thereof and insecticidal, acaricidal, fungicidal compositions | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1985-03-20 | — | — | EP | disclosed |