Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.54 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.54 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.54 |
| ▸ | SOST | Q9BQB4 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 4/20 | 0.49 |
| ▸ | CA2 | P00918 | 4/20 | 0.49 |
| ▸ | CA9 | Q16790 | 3/20 | 0.48 |
| ▸ | CA12 | O43570 | 2/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | NAMPT | P43490 | 1/20 | 0.44 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.42 |
| ▸ | KDM6B | O15054 | 1/20 | 0.42 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.42 |
| ▸ | HIF1AN | Q9NWT6 | 1/20 | 0.42 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.42 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9556140 | 0.85 | KMT2A (0.50) | MAPTKDM4ECA1CA2CA9 | |
| SCHEMBL28826070 | 0.80 | PLK1 (0.50) | MAPTCA1CA2CA9CA12 | |
| SCHEMBL432166 | 0.80 | CA1 (0.51) | MAPTKDM4ECA1CA2CA9 | |
| SCHEMBL11107537 | 0.79 | KDM4E (0.80) | MAPTKDM4EHIF1ASLC22A6SLC22A8 | |
| SCHEMBL14075727 | 0.78 | KDM4E (0.62) | MAPTKDM4EHIF1ASLC22A6SLC22A8 | |
| SCHEMBL25039608 | 0.78 | KDM4E (0.54) | MAPTKDM4EHIF1ASLC22A6SLC22A8 | |
| SCHEMBL4817527 | 0.76 | MAPT (0.51) | MAPTCA1CA2CA9CA12 | |
| SCHEMBL9823319 | 0.76 | ALDH1A1 (0.65) | KDM4ECA9CA12ATMNAMPT | |
| SCHEMBL18268222 | 0.76 | KDM4E (0.59) | MAPTKDM4EHIF1ASLC22A6SLC22A8 | |
| SCHEMBL6941062 | 0.76 | CACNA1B (0.62) | MAPTKDM4EHIF1ASLC22A6SLC22A8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0239362-B1 | ANTI-TUMOR AGENTS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-12-04 | — | — | EP | disclosed |