Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | MME | P08473 | 2/20 | 0.48 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.46 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.44 |
| ▸ | CTSK | P43235 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | NAAA | Q02083 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ACE | P12821 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9829305 | 1.00 | HCAR2 (0.50) | HCAR2HTTMMELPAR1LPAR3 | |
| SCHEMBL10125211 | 0.86 | HCAR2 (0.53) | HCAR2HTTLPAR1LPAR3OPRM1 | |
| SCHEMBL15912310 | 0.86 | HCAR2 (0.53) | HCAR2HTTLPAR1LPAR3OPRM1 | |
| SCHEMBL10125207 | 0.86 | HCAR2 (0.53) | HCAR2HTTLPAR1LPAR3OPRM1 | |
| SCHEMBL9830863 | 0.81 | CTSK (0.48) | HCAR2HTTMMELPAR1LPAR3 | |
| SCHEMBL9830861 | 0.81 | CTSK (0.48) | HCAR2HTTMMELPAR1LPAR3 | |
| SCHEMBL9828235 | 0.81 | CA1 (0.46) | HCAR2HTTLPAR1LPAR3OPRM1 | |
| SCHEMBL9828238 | 0.81 | CA1 (0.46) | HCAR2HTTLPAR1LPAR3OPRM1 | |
| SCHEMBL8290955 | 0.80 | HCAR2 (0.54) | HCAR2HTTLPAR1LPAR3OPRM1 | |
| SCHEMBL10152007 | 0.80 | HCAR2 (0.54) | HCAR2HTTLPAR1LPAR3OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0226304-B1 | COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC | SANKYO COMPANY LIMITED (JP) | 1991-08-28 | — | — | EP | disclosed |
| US-4757066-A | Reduces renal toxicity | SANKYO COMPANY LIMITED (JP) | 1988-07-12 | — | — | US | disclosed |
| EP-0226304-A1 | Composition containing a penem or carbapenem antibiotic | SANKYO COMPANY LIMITED (JP) | 1987-06-24 | — | — | EP | disclosed |