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SCHEMBL9829331

SCHEMBL9829331

CC(Cc1ccc(-c2nnn[nH]2)cc1)c1ccc(OCc2ccc3ccccc3n2)cc1.CC(Cc1ccc(OCc2ccc3ccccc3n2)cc1)c1cccc(-c2nnn[nH]2)c1

nearest known ligand 0.49

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ CYSLTR1 Q9Y271 12/20 0.49
▸ CYSLTR2 Q9NS75 9/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9828588 0.97 CYSLTR1 (0.51) CYSLTR1CYSLTR2
SCHEMBL10421971 0.94 CYSLTR1 (0.54) CYSLTR1CYSLTR2
SCHEMBL10421912 0.94 CYSLTR1 (0.54) CYSLTR1CYSLTR2
SCHEMBL10421959 0.91 CYSLTR1 (0.56) CYSLTR1CYSLTR2
SCHEMBL10420411 0.91 CYSLTR2 (0.51) CYSLTR1CYSLTR2
SCHEMBL9828490 0.89 CYSLTR1 (0.55) CYSLTR1CYSLTR2
SCHEMBL10422056 0.88 CYSLTR1 (0.56) CYSLTR1CYSLTR2
SCHEMBL10422017 0.87 CYSLTR1 (0.55) CYSLTR1CYSLTR2
SCHEMBL10421791 0.85 CYSLTR2 (0.56) CYSLTR1CYSLTR2
SCHEMBL10421067 0.84 CYSLTR1 (0.60) CYSLTR1CYSLTR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0395697-A4 QUINOLINE DERIVATIVES AS ANTAGONISTS OF LEUKOTRIENE D 4? — 1991-03-13 — — EP disclosed
EP-0395697-A1 QUINOLINE DERIVATIVES AS ANTAGONISTS OF LEUKOTRIENE D 4 RHONE-POULENC RORER INTERNATIONAL (HOLDINGS) INC. (US) 1990-11-07 — — EP disclosed
WO-1989004303-A1 QUINOLINE DERIVATIVES AS ANTAGONISTS OF LEUKOTRIENE D4 RORER INTERNATIONAL (OVERSEAS) INC. (US) 1989-05-18 — — WO disclosed