Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | XIAP | P98170 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9829399 | 1.00 | L3MBTL1 (0.58) | L3MBTL1ALDH1A1POLBTP53XIAP | |
| SCHEMBL8829934 | 0.98 | L3MBTL1 (0.56) | L3MBTL1ALDH1A1POLBTP53XIAP | |
| SCHEMBL9829897 | 0.98 | L3MBTL1 (0.56) | L3MBTL1ALDH1A1POLBTP53XIAP | |
| SCHEMBL9831322 | 0.82 | SMN1; SMN2 (0.59) | ALDH1A1POLBTP53KMT2ARECQL | |
| SCHEMBL7899963 | 0.82 | SMN1; SMN2 (0.59) | ALDH1A1POLBTP53KMT2ARECQL | |
| SCHEMBL9829571 | 0.81 | SMN1; SMN2 (0.57) | ALDH1A1TP53KMT2ARECQLLMNA | |
| SCHEMBL7890180 | 0.81 | SMN1; SMN2 (0.57) | ALDH1A1TP53KMT2ARECQLLMNA | |
| SCHEMBL6429877 | 0.80 | L3MBTL1 (0.46) | L3MBTL1ALDH1A1POLBTP53XIAP | |
| SCHEMBL6139318 | 0.79 | SMN1; SMN2 (0.46) | ALDH1A1POLBTP53KMT2ARECQL | |
| SCHEMBL10809127 | 0.79 | TP53 (0.48) | ALDH1A1POLBTP53KMT2ARECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0226304-B1 | COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC | SANKYO COMPANY LIMITED (JP) | 1991-08-28 | — | — | EP | disclosed |
| US-4757066-A | Reduces renal toxicity | SANKYO COMPANY LIMITED (JP) | 1988-07-12 | — | — | US | disclosed |
| US-4745124-A | THIO/ESTER PEPTIDES | UNIVERSITY OF MIAMI (US) | 1988-05-17 | — | — | US | disclosed |
| EP-0226304-A1 | Composition containing a penem or carbapenem antibiotic | SANKYO COMPANY LIMITED (JP) | 1987-06-24 | — | — | EP | disclosed |