Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 6/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CCR6 | P51684 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9829610 | 0.90 | PKM (0.53) | PKMNPSR1SMN1; SMN2HTTMAPT | |
| SCHEMBL9829695 | 0.89 | PKM (0.52) | PKMNPSR1SMN1; SMN2HTTMAPT | |
| SCHEMBL9828540 | 0.88 | PKM (0.56) | PKMNPSR1SMN1; SMN2HTTMAPT | |
| SCHEMBL9829256 | 0.84 | PKM (0.54) | PKMNPSR1SMN1; SMN2HTTMAPT | |
| SCHEMBL9830252 | 0.84 | PKM (0.54) | PKMNPSR1SMN1; SMN2HTTMAPT | |
| SCHEMBL9830675 | 0.83 | KDM4E (0.54) | PKMNPSR1SMN1; SMN2HTTMAPT | |
| SCHEMBL9245052 | 0.82 | PKM (0.62) | PKMNPSR1SMN1; SMN2HTTMAPT | |
| SCHEMBL9828192 | 0.81 | PKM (0.58) | PKMNPSR1SMN1; SMN2HTTMAPT | |
| SCHEMBL9828624 | 0.80 | PKM (0.60) | PKMNPSR1SMN1; SMN2HTTMAPT | |
| SCHEMBL9831364 | 0.80 | PKM (0.62) | PKMNPSR1SMN1; SMN2HTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0191736-B1 | USE OF QUINOLINE DERIVATIVES FOR THE PROTECTION OF CROP PLANTS | CIBA-GEIGY AG (CH) | 1991-07-17 | — | — | EP | claimed |
| US-4881966-A | PLANT SAFENING AGENTS | CIBA-GEIGY CORPORATION (US) | 1989-11-21 | — | — | US | disclosed |