SCHEMBL9829451

SCHEMBL9829451

[CH2]C(=N)N1CC/C(=N/O)C1

nearest known ligand 0.36

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CHRNA7 P36544 1/20 0.36
TSHR P16473 1/20 0.31
CASP1 P29466 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9829455 1.00 CHRNA7 (0.36) CHRNA7TSHRCASP1
SCHEMBL9829410 0.87 CHRNA7 (0.43) CHRNA7TSHRCASP1
Hydrochloric Acid SCHEMBL9836029 0.73 CHRNA7 (0.32) CHRNA7
Hydrochloric Acid SCHEMBL9836024 0.73 CHRNA7 (0.32) CHRNA7
Hydrochloric Acid SCHEMBL9836141 0.73 CHRNA7 (0.32) CHRNA7
Hydrochloric Acid SCHEMBL9836137 0.73 CHRNA7 (0.32) CHRNA7
SCHEMBL9059632 0.70 F2 (0.46) CHRNA7TSHRCASP1
SCHEMBL9385821 0.70 F2 (0.46) CHRNA7TSHRCASP1
Hydrochloric Acid SCHEMBL9834279 0.64 CHRNA7 (0.38) CHRNA7TSHRCASP1
Hydrochloric Acid SCHEMBL9833870 0.64 CHRNA7 (0.38) CHRNA7TSHRCASP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0226304-B1 COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC SANKYO COMPANY LIMITED (JP) 1991-08-28 EP claimed
US-4757066-A Reduces renal toxicity SANKYO COMPANY LIMITED (JP) 1988-07-12 US claimed
EP-0226304-A1 Composition containing a penem or carbapenem antibiotic SANKYO COMPANY LIMITED (JP) 1987-06-24 EP claimed
EP-0226304-B1 COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC SANKYO COMPANY LIMITED (JP) 1991-08-28 EP disclosed
US-4757066-A Reduces renal toxicity SANKYO COMPANY LIMITED (JP) 1988-07-12 US disclosed
EP-0226304-A1 Composition containing a penem or carbapenem antibiotic SANKYO COMPANY LIMITED (JP) 1987-06-24 EP disclosed