Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9829455 | 0.87 | CHRNA7 (0.36) | CHRNA7TSHRCASP1 | |
| SCHEMBL9829451 | 0.87 | CHRNA7 (0.36) | CHRNA7TSHRCASP1 | |
| SCHEMBL9059632 | 0.77 | F2 (0.46) | CHRNA7TSHRCASP1GAA | |
| SCHEMBL9385821 | 0.77 | F2 (0.46) | CHRNA7TSHRCASP1GAA | |
| Hydrochloric Acid SCHEMBL9833870 | 0.71 | CHRNA7 (0.38) | CHRNA7TSHRCASP1GAA | |
| Hydrochloric Acid SCHEMBL9834279 | 0.71 | CHRNA7 (0.38) | CHRNA7TSHRCASP1GAA | |
| SCHEMBL6512271 | 0.70 | CHRNA7 (0.45) | CHRNA7TSHRCASP1GAA | |
| SCHEMBL1114215 | 0.68 | CHRNA7 (0.48) | CHRNA7TSHRCASP1GAA | |
| SCHEMBL1114221 | 0.65 | — | — | |
| SCHEMBL15387052 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0226304-B1 | COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC | SANKYO COMPANY LIMITED (JP) | 1991-08-28 | — | — | EP | claimed |
| US-4757066-A | Reduces renal toxicity | SANKYO COMPANY LIMITED (JP) | 1988-07-12 | — | — | US | claimed |
| EP-0226304-A1 | Composition containing a penem or carbapenem antibiotic | SANKYO COMPANY LIMITED (JP) | 1987-06-24 | — | — | EP | claimed |
| EP-0226304-B1 | COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC | SANKYO COMPANY LIMITED (JP) | 1991-08-28 | — | — | EP | disclosed |
| US-4757066-A | Reduces renal toxicity | SANKYO COMPANY LIMITED (JP) | 1988-07-12 | — | — | US | disclosed |
| EP-0226304-A1 | Composition containing a penem or carbapenem antibiotic | SANKYO COMPANY LIMITED (JP) | 1987-06-24 | — | — | EP | disclosed |