SCHEMBL9829481

SCHEMBL9829481

CCC(O)c1cnc2ccccc2c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.49
LMNA P02545 3/20 0.48
PDGFRB P09619 2/20 0.44
PDGFRA P16234 2/20 0.44
MGAM O43451 1/20 0.44
RAB9A P51151 2/20 0.43
POLB P06746 1/20 0.43
TSHR P16473 1/20 0.43
HSD17B10 Q99714 1/20 0.43
PDE4D Q08499 2/20 0.43
ALDH1A1 P00352 2/20 0.43
PDE4A P27815 1/20 0.43
PDE4B Q07343 1/20 0.43
PDE4C Q08493 1/20 0.43
KMT2A Q03164 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
KDM4E B2RXH2 2/20 0.41
NQO1 P15559 1/20 0.41
MEN1 O00255 1/20 0.41
NPSR1 Q6W5P4 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6664822 0.85 CYP3A4 (0.49) CYP1A2LMNAPDGFRBPDGFRAMGAM
SCHEMBL18426974 0.83 CYP1A2 (0.52) CYP1A2LMNAPDGFRBPDGFRAMGAM
SCHEMBL14467508 0.83 CYP1A2 (0.52) CYP1A2LMNAPDGFRBPDGFRAMGAM
SCHEMBL6263374 0.81 CYP1A2 (0.53) CYP1A2PDGFRBPDGFRAMGAMRAB9A
SCHEMBL19688524 0.81 CYP1A2 (0.53) CYP1A2PDGFRBPDGFRAMGAMRAB9A
SCHEMBL372349 0.80 CYP1A2 (0.52) CYP1A2PDGFRBPDGFRAMGAMRAB9A
SCHEMBL13369227 0.80 CYP1A2 (0.53) CYP1A2LMNAPDGFRBPDGFRAMGAM
SCHEMBL17223981 0.80 CYP1A2 (0.49) CYP1A2LMNAPDGFRBPDGFRAMGAM
SCHEMBL1037164 0.80 CYP1A2 (0.53) CYP1A2LMNAPDGFRBPDGFRAMGAM
SCHEMBL2328850 0.80 KMT2A (0.44) CYP1A2LMNAPDGFRBPDGFRAMGAM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0227057-B1 PROCESS FOR THE PREPARATION OF SUBSTITUTED ALCANOLS IN 1-POSITION BY AROMATIC OR HETEROCYCLIC GROUPS BASF Aktiengesellschaft (DE) 1991-08-21 EP disclosed
US-4996324-A Reacting secondary alcohol with primary alcohol in presence of basic catalyst BASF AKTIENGESELLSCHAFT (DE) 1991-02-26 US disclosed
EP-0227057-A2 Process for the preparation of substituted alcanols in 1-position by aromatic or heterocyclic groups BASF Aktiengesellschaft (DE) 1987-07-01 EP disclosed