Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.65 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.59 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.56 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.56 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.54 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.50 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.49 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | NAMPT | P43490 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.44 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5655426 | 0.98 | NAAA (0.68) | NAAAEPHX1KEAP1NFE2L2EPHX2 | |
| SCHEMBL7897834 | 0.98 | NAAA (0.68) | NAAAEPHX1KEAP1NFE2L2EPHX2 | |
| SCHEMBL9831292 | 0.98 | NAAA (0.62) | NAAAEPHX1KEAP1NFE2L2EPHX2 | |
| SCHEMBL9830181 | 0.96 | NAAA (0.65) | NAAAEPHX1KEAP1NFE2L2EPHX2 | |
| SCHEMBL2678008 | 0.95 | NAAA (0.62) | NAAAEPHX1KEAP1NFE2L2EPHX2 | |
| SCHEMBL6502279 | 0.95 | NAAA (0.62) | NAAAEPHX1KEAP1NFE2L2EPHX2 | |
| SCHEMBL9831902 | 0.93 | NAAA (0.60) | NAAAEPHX1KEAP1NFE2L2EPHX2 | |
| SCHEMBL5902012 | 0.93 | NAAA (0.59) | NAAAEPHX1KEAP1NFE2L2EPHX2 | |
| SCHEMBL9830399 | 0.89 | PRMT1 (0.59) | NAAAEPHX1KEAP1NFE2L2EPHX2 | |
| SCHEMBL19359643 | 0.87 | NAAA (0.56) | NAAAEPHX1KEAP1NFE2L2EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0226304-B1 | COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC | SANKYO COMPANY LIMITED (JP) | 1991-08-28 | — | — | EP | disclosed |
| US-4757066-A | Reduces renal toxicity | SANKYO COMPANY LIMITED (JP) | 1988-07-12 | — | — | US | disclosed |
| EP-0226304-A1 | Composition containing a penem or carbapenem antibiotic | SANKYO COMPANY LIMITED (JP) | 1987-06-24 | — | — | EP | disclosed |