Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | PKM | P14618 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | POLB | P06746 | 4/20 | 0.45 |
| ▸ | BLM | P54132 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | CASP1 | P29466 | 3/20 | 0.45 |
| ▸ | CASP7 | P55210 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7253210 | 0.81 | CYP19A1 (0.72) | MAPTHSD17B10ALDH1A1CYP19A1KDM4E | |
| SCHEMBL10144382 | 0.78 | CYP19A1 (0.50) | MAPTHSD17B10ALDH1A1CYP19A1KDM4E | |
| SCHEMBL21823786 | 0.78 | CYP19A1 (0.50) | MAPTHSD17B10ALDH1A1CYP19A1KDM4E | |
| Hydrochloric Acid SCHEMBL27350547 | 0.76 | CYP19A1 (0.49) | MAPTHSD17B10ALDH1A1CYP19A1KDM4E | |
| Hydrochloric Acid SCHEMBL27339401 | 0.76 | CYP19A1 (0.49) | MAPTHSD17B10ALDH1A1CYP19A1KDM4E | |
| SCHEMBL16767195 | 0.75 | MAPT (0.65) | MAPTHSD17B10ALDH1A1CYP19A1KDM4E | |
| SCHEMBL21823775 | 0.74 | PIM1 (0.55) | MAPTHSD17B10ALDH1A1CYP19A1KDM4E | |
| SCHEMBL513242 | 0.74 | ALDH1A1 (0.53) | MAPTHSD17B10ALDH1A1CYP19A1KDM4E | |
| SCHEMBL17773148 | 0.74 | CYP19A1 (0.46) | MAPTHSD17B10ALDH1A1CYP19A1KDM4E | |
| SCHEMBL12190539 | 0.74 | CYP19A1 (0.46) | MAPTHSD17B10ALDH1A1CYP19A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0321115-B1 | CARBOXAMIDE DERIVATIVES HAVING TETRAZOLE AND THIAZOLE RINGS AND THEIR USE | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1991-08-14 | — | — | EP | disclosed |
| US-4946855-A | ANTIALLERGIC | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1990-08-07 | — | — | US | disclosed |
| EP-0321115-A1 | Carboxamide derivatives having tetrazole and thiazole rings and their use | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1989-06-21 | — | — | EP | disclosed |