Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.49 |
| ▸ | TRPA1 | O75762 | 6/20 | 0.45 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.42 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.41 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | ALPL | P05186 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | TRPM8 | Q7Z2W7 | 3/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9831253 | 0.91 | NOTUM (0.46) | TRPA1NOTUMNR1H2NR1H3NPC1 | |
| SCHEMBL6450108 | 0.84 | DCUN1D1 (0.46) | DCUN1D1TRPA1NR1H2NR1H3NPC1 | |
| SCHEMBL9832700 | 0.84 | TRPA1 (0.48) | DCUN1D1TRPA1NOTUMNR1H2NR1H3 | |
| SCHEMBL9831523 | 0.84 | NR1H2 (0.57) | DCUN1D1TRPA1NOTUMNR1H2NR1H3 | |
| SCHEMBL3183369 | 0.75 | HSD17B10 (0.63) | NOTUMNPC1CYP1A2ALPLCYP3A4 | |
| SCHEMBL21657871 | 0.73 | NOTUM (0.45) | TRPA1NOTUMCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL6454617 | 0.72 | JAK2 (0.40) | TRPA1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL27925987 | 0.72 | KCNN4 (0.49) | TRPA1NOTUMCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL6454714 | 0.72 | ADORA2A (0.53) | DCUN1D1NR1H2NR1H3NPC1TP53 | |
| SCHEMBL6456566 | 0.72 | NR1H2 (0.53) | DCUN1D1TRPA1NR1H2NR1H3NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0185256-B1 | TRIAZOLE DERIVATES, THEIR PREPARATION AND THEIR USE AS PESTICIDES | CIBA-GEIGY AG (CH) | 1991-01-30 | — | — | EP | disclosed |
| US-4788210-A | PESTICIDES | HOFFMANN-LA ROCHE INC. (US) | 1988-11-29 | — | — | US | disclosed |
| EP-0185256-A2 | Triazole derivates, their preparation and their use as pesticides | CIBA-GEIGY AG (CH) | 1986-06-25 | — | — | EP | disclosed |