⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3692164 | 0.80 | — | — | |
| SCHEMBL8392292 | 0.77 | — | — | |
| SCHEMBL127102 | 0.75 | — | — | |
| Fluoride SCHEMBL29092358 | 0.73 | TSHR (0.48) | — | |
| SCHEMBL138654 | 0.73 | — | — | |
| Fluoride SCHEMBL28481354 | 0.73 | TSHR (0.48) | — | |
| SCHEMBL1014047 | 0.73 | — | — | |
| SCHEMBL269512 | 0.73 | — | — | |
| SCHEMBL276923 | 0.73 | — | — | |
| Ammonia Solution, Strong SCHEMBL21462229 | 0.73 | TSHR (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0226304-B1 | COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC | SANKYO COMPANY LIMITED (JP) | 1991-08-28 | — | — | EP | disclosed |
| US-4757066-A | Reduces renal toxicity | SANKYO COMPANY LIMITED (JP) | 1988-07-12 | — | — | US | disclosed |
| EP-0226304-A1 | Composition containing a penem or carbapenem antibiotic | SANKYO COMPANY LIMITED (JP) | 1987-06-24 | — | — | EP | disclosed |