SCHEMBL8392292

SCHEMBL8392292

CC#CCCCC(C)C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10357187 0.92 LMNA (0.43)
SCHEMBL1132741 0.82
SCHEMBL9371674 0.80 LMNA (0.56)
SCHEMBL2118687 0.79 LMNA (0.36)
SCHEMBL4525081 0.79
SCHEMBL2118223 0.79
SCHEMBL9547960 0.78 LMNA (0.39)
SCHEMBL9829967 0.77
SCHEMBL4510255 0.76 TSHR (0.43)
SCHEMBL9547931 0.76 LMNA (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2610249-B1 PLURIPOTENT STEM CELL CARDIOMYOCYTE DIFFERENTIATION-PROMOTING AGENT UNIV KYOTO (JP) 2017-10-11 EP disclosed
US-5965611-A TREATING CHRONIC PERIPHERAL ARTERIAL OCCLUSION BY ADMINISTERING EMULSION COMPRISING ISOCARBACYCLIN, VEGETABLE OIL, PHOSPHOLIPID, AND WATER TEIGIN LIMITED (JP) 1999-10-12 US disclosed
EP-0634171-B1 PHARMACEUTICAL COMPOSITION FOR TREATING CEREBRAL THROMBOSIS TEIJIN LTD (JP) 1999-05-06 EP disclosed
EP-0761225-A1 PHARMACEUTICAL COMPOSITION FOR TREATING PERIPHERAL CIRCULATION DISORDER TEIJIN LIMITED (JP) 1997-03-12 EP disclosed
US-5610182-A ADMINISTERING AN ISOCARBACYCLIN OF SPECIFIC STRUCTURE IN THE FORM OF A FAT EMULSION TEIJIN, LIMITED (JP) 1997-03-11 US disclosed
EP-0634171-A1 PHARMACEUTICAL COMPOSITION FOR TREATING CEREBRAL THROMBOSIS TEIJIN LIMITED (JP) 1995-01-18 EP disclosed
EP-0389162-B1 2,5,6,7-Tetranor-4,8-inter-m-phenylene PGI2 derivatives TORAY INDUSTRIES (JP) 1993-12-08 EP disclosed
EP-0274064-B1 2,5,6,7-TETRANOR-18,18,19,19-TETRADEHYDRO-4,8-INTER-M-PHENYLENE PGI2 DERIVATIVES TORAY INDUSTRIES, INC. (JP) 1992-03-18 EP disclosed
US-5086071-A Improved chemical stability and ppotent in vivo TORAY INDUSTRIES, INC. (JP) 1992-02-04 US disclosed
EP-0232776-B1 2,5,6,7-TETRANOR-4,8-INTER-M-PHENYLENE PGI2 DERIVATIVES TORAY INDUSTRIES, INC. (JP) 1990-10-24 EP disclosed
EP-0389162-A1 2,5,6,7-Tetranor-4,8-inter-m-phenylene PGI2 derivatives TORAY INDUSTRIES, INC. (JP) 1990-09-26 EP disclosed
US-4880939-A ANTISECRETORY AGENTS, HYPOTENSIVES, ANTICOAGULANTS TORAY INDUSTRIES (JP) 1989-11-14 US disclosed
US-4775692-A ANTILIPEMIC, ANTICOAGULANT, HYPOTENSIVE, ANTISECRETORY AND ANTIULCER AGENT TORAY INDUSTRIES, INC. (JP) 1988-10-04 US disclosed
EP-0274064-A2 2,5,6,7-Tetranor-18,18,19,19-tetradehydro-4,8-inter-m-phenylene PGI2 derivatives TORAY INDUSTRIES, INC. (JP) 1988-07-13 EP disclosed
EP-0232776-A2 2,5,6,7-tetranor-4,8-inter-m-phenylene PGI2 derivatives TORAY INDUSTRIES, INC. (JP) 1987-08-19 EP disclosed