⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10531422 | 0.89 | — | — | |
| SCHEMBL17934318 | 0.81 | — | — | |
| SCHEMBL8234341 | 0.81 | — | — | |
| SCHEMBL1742203 | 0.73 | — | — | |
| SCHEMBL1629925 | 0.72 | PHGDH (0.42) | — | |
| SCHEMBL14573053 | 0.69 | CARM1 (0.44) | — | |
| SCHEMBL13400 | 0.69 | — | — | |
| SCHEMBL1109080 | 0.69 | — | — | |
| SCHEMBL3336982 | 0.67 | — | — | |
| SCHEMBL13750467 | 0.67 | CYP2D6 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3700911-B1 | NOVEL MACROCYCLIC DERIVATIVES, PROCESS FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | SERVIER LAB (FR) | 2023-09-06 | — | — | EP | disclosed |
| US-20180042902-A1 | Heterocyclic Compounds and Uses Thereof | INTELLIKINE, LLC | 2018-02-15 | — | — | US | disclosed |
| US-9682141-B2 | Combination of kinase inhibitors and uses thereof | INTELLIKINE LLC (US) | 2017-06-20 | — | — | US | disclosed |
| EP-2288601-B1 | BICYCLYLARYL-ARYL-AMINE COMPOUNDS AND THEIR USE | CANCER REC TECH LTD (GB) | 2014-10-15 | — | — | EP | disclosed |
| WO-2009126535-A1 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF GPR119 ACTIVITY | IRM LLC (BM) | 2009-10-15 | — | — | WO | disclosed |
| EP-0307303-B1 | 1-[(2-Pyrimidinyl)-aminoalkyl] piperidines, their preparation and their use in therapy | SYNTHELABO (FR) | 1991-12-04 | — | — | EP | disclosed |
| EP-0307303-A1 | 1-[(2-Pyrimidinyl)-aminoalkyl] piperidines, their preparation and their use in therapy | SYNTHELABO (FR) | 1989-03-15 | — | — | EP | disclosed |