Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17637932 | 0.77 | TDP1 (0.58) | TDP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL10848782 | 0.73 | ALDH1A1 (0.42) | TDP1ALDH1A1 | |
| SCHEMBL8356440 | 0.73 | TDP1 (0.48) | TDP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL1591739 | 0.71 | ALDH1A1 (0.40) | TDP1ALDH1A1CYP2C19 | |
| SCHEMBL13254368 | 0.71 | TDP1 (0.40) | TDP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL3224348 | 0.70 | CYP2C19 (0.58) | TDP1ALDH1A1CYP2C19 | |
| SCHEMBL3217572 | 0.70 | TDP1 (0.50) | TDP1ALDH1A1 | |
| SCHEMBL25682838 | 0.70 | TDP1 (0.50) | TDP1ALDH1A1 | |
| SCHEMBL12286282 | 0.70 | TDP1 (0.43) | TDP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL15249460 | 0.70 | TDP1 (0.74) | TDP1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0261248-B1 | $g(a), $g(a)-TREHALOSE TRIMYCOLATE AND MEDICINAL COMPOSITION | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1991-05-29 | — | — | EP | disclosed |