Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | MMP2 | P08253 | 2/20 | 0.32 |
| ▸ | CA9 | Q16790 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GMNN | O75496 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3881590 | 0.96 | SHBG (0.43) | SHBGEPHX1CA12CA1CA2 | |
| SCHEMBL466377 | 0.93 | SHBG (0.48) | SHBGEPHX1CA12CA1CA2 | |
| SCHEMBL7366600 | 0.93 | SHBG (0.48) | SHBGEPHX1CA12CA1CA2 | |
| SCHEMBL3860192 | 0.93 | SHBG (0.48) | SHBGEPHX1CA12CA1CA2 | |
| SCHEMBL483020 | 0.93 | SHBG (0.48) | SHBGEPHX1CA12CA1CA2 | |
| Ethane SCHEMBL11269854 | 0.90 | SHBG (0.46) | SHBGEPHX1CA12CA1CA2 | |
| SCHEMBL11043449 | 0.90 | SHBG (0.39) | SHBGEPHX1CA12CA1CA2 | |
| Ammonia Solution, Strong SCHEMBL7990121 | 0.90 | SHBG (0.46) | SHBGEPHX1CA12CA1CA2 | |
| Ammonia Solution, Strong SCHEMBL6306401 | 0.90 | SHBG (0.46) | SHBGEPHX1CA12CA1CA2 | |
| Methane SCHEMBL11266020 | 0.90 | SHBG (0.46) | SHBGEPHX1CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0422178-A1 | PYRIMIDINE DERIVATIVES. | ICI PLC (GB) | 1991-04-17 | — | — | EP | claimed |