Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 2/20 | 0.62 |
| ▸ | CTSK | P43235 | 2/20 | 0.60 |
| ▸ | CTSL | P07711 | 2/20 | 0.60 |
| ▸ | CTSB | P07858 | 2/20 | 0.60 |
| ▸ | MME | P08473 | 2/20 | 0.60 |
| ▸ | ECE1 | P42892 | 2/20 | 0.60 |
| ▸ | CTSS | P25774 | 1/20 | 0.60 |
| ▸ | TACR1 | P25103 | 2/20 | 0.58 |
| ▸ | REN | P00797 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1436898 | 1.00 | CAPN1 (0.62) | CAPN1CTSKCTSLCTSBMME | |
| SCHEMBL4402534 | 0.96 | CAPN1 (0.59) | CAPN1CTSKCTSLCTSBMME | |
| SCHEMBL4402523 | 0.96 | CAPN1 (0.59) | CAPN1CTSKCTSLCTSBMME | |
| Carbon Dioxide SCHEMBL2254435 | 0.96 | CTSK (0.60) | CAPN1CTSKCTSLCTSBMME | |
| SCHEMBL29576951 | 0.95 | MME (0.63) | CAPN1CTSKCTSLCTSBMME | |
| SCHEMBL6379430 | 0.94 | CAPN1 (0.65) | CAPN1CTSKCTSLCTSBCTSS | |
| SCHEMBL16462972 | 0.93 | PPARA (0.56) | CAPN1CTSKCTSLCTSBMME | |
| SCHEMBL31607495 | 0.93 | CTSK (0.60) | CAPN1CTSKCTSLCTSBMME | |
| SCHEMBL16462974 | 0.93 | PPARA (0.56) | CAPN1CTSKCTSLCTSBMME | |
| SCHEMBL9359914 | 0.92 | CTSK (0.60) | CAPN1CTSKCTSLCTSBCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0226304-B1 | COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC | SANKYO COMPANY LIMITED (JP) | 1991-08-28 | — | — | EP | disclosed |
| US-4757066-A | Reduces renal toxicity | SANKYO COMPANY LIMITED (JP) | 1988-07-12 | — | — | US | disclosed |
| EP-0226304-A1 | Composition containing a penem or carbapenem antibiotic | SANKYO COMPANY LIMITED (JP) | 1987-06-24 | — | — | EP | disclosed |
| US-4341707-A | CHEMICAL INTERMEDIATES; PEPTIDE SYNTHESIS | Ogura, Haruo (JP) | 1982-07-27 | — | — | US | disclosed |