⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL680633 | 0.82 | — | — | |
| SCHEMBL12204156 | 0.82 | GABBR2 (0.40) | — | |
| SCHEMBL901700 | 0.79 | — | — | |
| SCHEMBL1239420 | 0.78 | — | — | |
| SCHEMBL12711981 | 0.78 | GABBR2 (0.38) | — | |
| SCHEMBL21414067 | 0.78 | — | — | |
| Hydrochloric Acid SCHEMBL3707991 | 0.76 | GABBR2 (0.41) | — | |
| SCHEMBL14295828 | 0.75 | GABBR2 (0.40) | — | |
| SCHEMBL21891485 | 0.75 | GABBR2 (0.36) | — | |
| SCHEMBL22320216 | 0.75 | GABBR2 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0199281-B1 | PYRIDAZINONE DERIVATIVES, PREPARATION THEREOF, AND INSECTICIDAL, ACARICIDAL, NEMATICIDAL, FUNGICIDAL COMPOSITIONS | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1991-07-10 | — | — | EP | disclosed |
| US-4837217-A | Pyridazinone derivatives, preparation thereof, and insecticidal, acaricidal, nematicidal, fungicidal compositions | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1989-06-06 | — | — | US | disclosed |
| CN-86102700-A | The preparation method of pyridazinone derivative and desinsection thereof, kill mite, nematicide, fungicide composition | — | 1986-12-17 | — | — | CN | disclosed |
| EP-0199281-A2 | Pyridazinone derivatives, preparation thereof, and insecticidal, acaricidal, nematicidal, fungicidal compositions | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1986-10-29 | — | — | EP | disclosed |