Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 1/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.54 |
| ▸ | PLK1 | P53350 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.50 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.50 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.50 |
| ▸ | CTSB | P07858 | 2/20 | 0.48 |
| ▸ | CTSV | O60911 | 1/20 | 0.48 |
| ▸ | CTSL | P07711 | 1/20 | 0.48 |
| ▸ | CTSS | P25774 | 1/20 | 0.48 |
| ▸ | ELANE | P08246 | 2/20 | 0.48 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.48 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.47 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9830741 | 1.00 | MMP3 (0.54) | MMP3HDAC8PLK1HPGDALDH1A1 | |
| SCHEMBL18067781 | 0.87 | PLK1 (0.55) | MMP3HDAC8PLK1HPGDALDH1A1 | |
| SCHEMBL9828917 | 0.87 | MMP3 (0.53) | MMP3HDAC8PLK1HPGDALDH1A1 | |
| SCHEMBL18067787 | 0.87 | PLK1 (0.55) | MMP3HDAC8PLK1HPGDALDH1A1 | |
| SCHEMBL9828925 | 0.87 | MMP3 (0.53) | MMP3HDAC8PLK1HPGDALDH1A1 | |
| SCHEMBL18067772 | 0.87 | PLK1 (0.55) | MMP3HDAC8PLK1HPGDALDH1A1 | |
| SCHEMBL2330556 | 0.86 | MMP3 (0.49) | MMP3HDAC8PLK1HPGDALDH1A1 | |
| SCHEMBL10659462 | 0.86 | MMP3 (0.49) | MMP3HDAC8PLK1HPGDALDH1A1 | |
| SCHEMBL4797956 | 0.85 | HRH4 (0.58) | MMP3HDAC8PLK1HPGDALDH1A1 | |
| SCHEMBL9716712 | 0.85 | ELANE (0.64) | CTSBCTSVCTSLCTSSELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0226304-B1 | COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC | SANKYO COMPANY LIMITED (JP) | 1991-08-28 | — | — | EP | disclosed |
| US-4757066-A | Reduces renal toxicity | SANKYO COMPANY LIMITED (JP) | 1988-07-12 | — | — | US | disclosed |
| EP-0226304-A1 | Composition containing a penem or carbapenem antibiotic | SANKYO COMPANY LIMITED (JP) | 1987-06-24 | — | — | EP | disclosed |