⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxazole SCHEMBL14 | 0.96 | — | — | |
| Oxazole SCHEMBL29728171 | 0.96 | — | — | |
| Oxazole SCHEMBL1743576 | 0.96 | — | — | |
| Oxazole SCHEMBL7538737 | 0.93 | — | — | |
| Oxazole SCHEMBL986132 | 0.93 | — | — | |
| Oxazole SCHEMBL3864385 | 0.93 | — | — | |
| Oxazole SCHEMBL9452923 | 0.93 | — | — | |
| Oxazole SCHEMBL1128503 | 0.93 | — | — | |
| Oxazole SCHEMBL5199619 | 0.93 | — | — | |
| Oxazole SCHEMBL6315939 | 0.93 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119912452-A | Preparation method of triazine diketone compound with high chiral purity | 天津辰欣药物研究有限公司 | 2025-05-02 | — | — | CN | claimed |
| CN-116924925-A | Method for synthesizing tetracaine by reducing amine | 西南石油大学 | 2023-10-24 | — | — | CN | claimed |
| CN-114773279-A | Novel synthesis method of metconazole | 浙江工业大学 | 2022-07-22 | — | — | CN | claimed |
| CN-109053567-B | Method for reducing nitrogen-containing heterocyclic compound by hydrogen transfer | 西南石油大学 | 2021-09-21 | — | — | CN | claimed |
| CN-108069863-B | Method for synthesizing norepinephrine | 武汉武药制药有限公司 | 2020-08-11 | — | — | CN | claimed |
| CN-110143944-A | A kind of preparation method of chiral benzhydryl simultaneously [b, e] thia * -11- alcohol | 上海升华医药科技有限公司 | 2019-08-20 | — | — | CN | claimed |
| CN-109320485-A | Method for synthesizing tegolazan chiral alcohol | 海门慧聚药业有限公司 | 2019-02-12 | — | — | CN | claimed |
| CN-108602808-A | Method for synthesizing nebivolol intermediate | 曼纳里尼国际经营卢森堡有限公司 | 2018-09-28 | — | — | CN | claimed |
| CN-103998423-B | The preparation method of travoprost | 奇诺因药物和化学工厂私人有限公司 | 2018-04-27 | — | — | CN | claimed |
| CN-104379566-A | Indacaterol intermediate and method for synthesizing indacaterol | SHANGHAI VIWIT PHARMACEUTICAL CO LTD | 2015-02-25 | — | — | CN | claimed |
| CN-102942525-B | Method for preparing polyisocyanate containing uretidione group | YANTAI WANHUA POLYURETHANES CO | 2014-08-06 | — | — | CN | claimed |
| CN-103214493-A | Method for generating narcotine by selective reduction utilizing chiral boron catalyst | NANJING ACESYS PHARMATECH CO LTD | 2013-07-24 | — | — | CN | claimed |
| CN-101519374-B | Method for synthesizing derivatives of chiral pyridyl aminoalcohols, and intermediate products and final products of same | ASYMCHEM LAB TIANJIN CO LTD | 2013-05-15 | — | — | CN | claimed |
| CN-102942525-A | Method for preparing polyisocyanate containing uretidione group | YANTAI WANHUA POLYURETHANES CO | 2013-02-27 | — | — | CN | claimed |
| CN-102688779-A | Preparation of phosphine ligand ruthenium catalyst and application thereof in asymmetric reduction | ASYMCHEM LAB TIANJIN CO LTD | 2012-09-26 | — | — | CN | claimed |
| CN-101835731-A | Accelerated reduction of organic substances with boranes | BASF SE | 2010-09-15 | — | — | CN | claimed |
| CN-101720186-A | Compositions of (-)-e-10-oh-nt and methods for their synthesis and use | ADOLOR CORP | 2010-06-02 | — | — | CN | claimed |
| CN-1135217-A | Process for prepn. of (S)-1-[2(S)-(1,3-dihydro-1,3-dioxo-isoindo-2-yl)-1-oxo-3-phenylpropyl]-1,2,3,4-tetrahydro-2-pyridine-carboxylic acid methyl ester | MERRELL DOW PHARMA (US) | 1996-11-06 | — | — | CN | claimed |
| CN-119912452-A | Preparation method of triazine diketone compound with high chiral purity | 天津辰欣药物研究有限公司 | 2025-05-02 | — | — | CN | disclosed |
| CN-1135217-A | Process for prepn. of (S)-1-[2(S)-(1,3-dihydro-1,3-dioxo-isoindo-2-yl)-1-oxo-3-phenylpropyl]-1,2,3,4-tetrahydro-2-pyridine-carboxylic acid methyl ester | MERRELL DOW PHARMA (US) | 1996-11-06 | — | — | CN | disclosed |