Oxazole

Oxazole

SCHEMBL986132

N.c1cocn1

nearest known ligand 0.00

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⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Oxazole SCHEMBL27640016 0.97
Oxazole SCHEMBL1743576 0.96
Oxazole SCHEMBL29728171 0.96
Oxazole SCHEMBL14 0.96
Oxazole SCHEMBL983076 0.93
Oxazole SCHEMBL1128503 0.93
Oxazole SCHEMBL5199619 0.93
Oxazole SCHEMBL9452923 0.93
Oxazole SCHEMBL3864385 0.93
Oxazole SCHEMBL645202 0.93

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 89 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115820099-A Solvent-free polyaspartate polyurea coating and preparation method thereof 中海油常州涂料化工研究院有限公司 2023-03-21 CN claimed
EP-0713868-B1 Process for the manufacture of insecticidal arylpyrroles via oxazole amine intermediates BASF AG (DE) 2002-01-16 EP claimed
US-5574175-A Process for the manufacture of insecticidal arylpyrroles via oxazole amine intermediates AMERICAN CYANAMID CO. (US) 1996-11-12 US claimed
CN-1133836-A Process for manufacture of insecticidal arylpyrrolwa via oxazole amine intermediates AMERICAN CYANAMID CO (US) 1996-10-23 CN claimed
EP-0713868-A1 Process for the manufacture of insecticidal arylpyrroles via oxazole amine intermediates American Cyanamid Company (US) 1996-05-29 EP claimed
JP-10067760-A None JP disclosed
CN-118140931-A Application of chromene-thiazole/oxazolamine compound 贵州医科大学 2024-06-07 CN disclosed
US-20230091297-A1 INHIBITORS OF HSP70 PROTEINS ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA 2023-03-23 US disclosed
CN-115820099-A Solvent-free polyaspartate polyurea coating and preparation method thereof 中海油常州涂料化工研究院有限公司 2023-03-21 CN disclosed
CN-113825498-A Improved lyophilized formulations comprising hyaluronic acid and plasma proteins and uses thereof 骨治疗公司 2021-12-21 CN disclosed
WO-2021183942-A1 INHIBITORS OF HSP70 PROTEINS ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) 2021-09-16 WO disclosed
US-10844044-B2 WDR5 inhibitors and modulators VANDERBILT UNIVERSITY (US) 2020-11-24 US disclosed
EP-0713868-A1 Process for the manufacture of insecticidal arylpyrroles via oxazole amine intermediates American Cyanamid Company (US) 1996-05-29 EP disclosed
EP-0713868-A1 Process for the manufacture of insecticidal arylpyrroles via oxazole amine intermediates American Cyanamid Company (US) 1996-05-29 EP disclosed
CN-1108683-A Compound additive for gasoline CHINA PETROL CHEMICAL MARKETIN (CN) 1995-09-20 CN disclosed
US-5446170-A Reacting oxazole amine intermediate with halonitrile in presence of base AMERICAN CYANAMID COMPANY (US) 1995-08-29 US disclosed
US-5446170-A Reacting oxazole amine intermediate with halonitrile in presence of base AMERICAN CYANAMID COMPANY (US) 1995-08-29 US disclosed
WO-1994010160-A9 NOVEL AZIDE-CONTAINING CHELATORS WHOSE AFFINITY FOR CALCIUM ION IS DECREASED BY ILLUMINATION 1994-08-18 WO disclosed
WO-1994010160-A1 NOVEL AZIDE-CONTAINING CHELATORS WHOSE AFFINITY FOR CALCIUM ION IS DECREASED BY ILLUMINATION THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1994-05-11 WO disclosed
US-5162360-A Treating hypercholesterolemia and atherosclerosis; ACAT acyl-coenzyme A:-cholesterol acyltransferase WARNER-LAMBERT COMPANY (US) 1992-11-10 US disclosed