SCHEMBL98309

SCHEMBL98309

NOC(c1ccccc1)c1ccccc1

nearest known ligand 0.74

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 20/20 0.74
TDO2 P48775 20/20 0.74
IDO2 Q6ZQW0 3/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7227619 0.97 IDO1 (0.75) IDO1TDO2IDO2
SCHEMBL98113 0.86 IDO1 (0.64) IDO1TDO2IDO2
SCHEMBL14041261 0.86 IDO1 (0.83) IDO1TDO2IDO2
SCHEMBL14041192 0.86 IDO1 (1.00) IDO1TDO2IDO2
SCHEMBL127629 0.75 IDO1 (0.46) IDO1TDO2IDO2
SCHEMBL27280965 0.75 IDO1 (0.46) IDO1TDO2IDO2
Methane SCHEMBL29089947 0.73 IDO1 (0.44) IDO1TDO2IDO2
Water SCHEMBL11878861 0.73 IDO1 (0.44) IDO1TDO2IDO2
Ammonia Solution, Strong SCHEMBL7282272 0.73 IDO1 (0.44) IDO1TDO2IDO2
SCHEMBL29233222 0.72 IDO1 (0.45) IDO1TDO2IDO2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 163 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2227233-B1 IDO INHIBITORS NEWLINK GENETICS (US) 2013-02-13 EP claimed
US-20110053941-A1 IDO Inhibitors NEWLINK GENETICS (US) 2011-03-03 US claimed
EP-2227233-A2 IDO INHIBITORS Newlink Genetics (US) 2010-09-15 EP claimed
WO-2009073620-A2 IDO INHIBITORS NEWLINK GENETICS (US) 2009-06-11 WO claimed
US-20090136461-A1 Neuronal differentiation method of adult stem cells using small molecules KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2009-05-28 US claimed
US-6048707-A ANALYZING STRUCTURAL RELATIONSHIP BETWEEN MONOSACCHARIDES OF CARBOHYDRATE; DERIVATIZING CARBOHYDRATE, CONVERTING TO MONOSACCHARIDES, FORMING LABELED MONOSACCHARIDES, SEPARATING MONOSACCHARIDES BY ELECTROPHORESIS, DETECTING MONOSACCARIDES GLYKO, INC. (US) 2000-04-11 US claimed
US-20240218170-A1 POLYIMIDE RESIN COMPOSITION, POLYIMIDE-BASED ADHESIVE COMPOSITION, POLYIMIDE ADHESIVE FILM, AND FLEXIBLE METAL CLAD LAMINATE FILM NEXFLEX CO., LTD. (KR) 2024-07-04 US disclosed
EP-3011961-B1 4F-BENZOYL-TN14003 FOR THE MOBILISATION OF HEMATOPOIETIC PROGENITOR CELLS IN VIEW OF TRANSPLANTATION BIOKINE THERAPEUTICS LTD (IL) 2020-11-11 EP disclosed
EP-2841084-B1 CXCR4 ANTAGONIST PEPTIDE FOR USE IN THE TREATMENT OF LARGE CELL LUNG CANCER BIOKINE THERAPEUTICS LTD (IL) 2018-05-30 EP disclosed
US-9439942-B2 Peptides and use thereof in the treatment of large cell lung cancer BIOKINE THERAPEUTICS LTD. (IL) 2016-09-13 US disclosed
US-9427456-B2 Peptide therapy for increasing platelet levels BIOKINE THERAPEUTICS LTD. (IL) 2016-08-30 US disclosed
EP-3011961-A1 4F-benzoyl-TN14003 for the mobilisation of hematopoietic progenitor cells in view of transplantation Biokine Therapeutics LTD. (IL) 2016-04-27 EP disclosed
EP-2942059-A1 4F-BENZOYL-TN14003 FOR USE IN THE TREATMENT OF MULTIPLE MYELOMA Biokine Therapeutics LTD. (IL) 2015-11-11 EP disclosed
WO-1992002495-A1 CYCLOPENTANE DERIVATIVES, PROCESS FOR PRODUCING THEM AND THEIR PHARMACEUTICAL USE SCHERING AKTIENGESELLSCHAFT BERLIN/BERGKAMEN (DE) 1992-02-20 WO disclosed
WO-1992002494-A1 CYCLOPENTANE DERIVATIVES, PROCESS FOR PRODUCING THEM AND THEIR PHARMACEUTICAL USE SCHERING AKTIENGESELLSCHAFT BERLIN/BERGKAMEN (DE) 1992-02-20 WO disclosed
EP-0462531-A2 Cyclic polypeptide with antibiotic activity, process for its preparation and pure culture of a Coelomycetes strain FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1991-12-27 EP disclosed
WO-1991014675-A1 BICYCLO[3.3.)]OCTANE DERIVATIVES, PROCESS FOR PRODUCING THEM AND THEIR PHARMACEUTICAL USE SCHERING AKTIENGESELLSCHAFT BERLIN UND BERGKAMEN (DE) 1991-10-03 WO disclosed
EP-0386487-A1 Novel N-(substituted aryl)-N'-(substituted alkoxy)-ureas and thioureas as antihypercholesterolemic and antiatherosclerotic agents WARNER-LAMBERT COMPANY (US) 1990-09-12 EP disclosed
US-4923896-A N-(substituted aryl)-N'-(substituted alkoxy)-ureas and thioureas as antihypercholesterolemic and antiatherosclerotic agents WARNER-LAMBERT COMPANY (US) 1990-05-08 US disclosed
US-4385177-A Cephalosporins having a carbamoylalkoxyiminoarylacetamido group at 7-position GLAXO LABORATORIES, LTD. (GB) 1983-05-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110053941-A1 IDO Inhibitors IDO1, IDO2, INMT IDO1 1/4885TDO2 4/4885IDO2 2/4885
US-20090136461-A1 Neuronal differentiation method of adult stem cells using small molecules DCX, NES, GAP43 IDO1 4046/4885TDO2 4800/4885IDO2 3523/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.