Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9833055 | 0.80 | KDM4E (0.41) | KDM4EALDH1A1LMNACHRM2CHRM4 | |
| SCHEMBL9831889 | 0.64 | MAPT (0.32) | LMNACHRM2CHRM4CHRM5THRB | |
| SCHEMBL2420231 | 0.61 | CHRM3 (0.58) | KDM4EALDH1A1LMNACHRM2CHRM4 | |
| SCHEMBL27463224 | 0.60 | TSHR (0.37) | KDM4EALDH1A1LMNAMAPTHTT | |
| SCHEMBL5857909 | 0.59 | PTPN1 (0.49) | KDM4EALDH1A1LMNACHRM2CHRM4 | |
| SCHEMBL23627241 | 0.56 | CHRM3 (0.44) | KDM4EALDH1A1L3MBTL1LMNACHRM2 | |
| SCHEMBL4141860 | 0.56 | CA1 (0.58) | KDM4EALDH1A1LMNAMAPTHTT | |
| SCHEMBL7002090 | 0.56 | CYP1A2 (0.40) | KDM4ELMNAMAPTHTTMEN1 | |
| SCHEMBL7002092 | 0.56 | TSHR (0.39) | KDM4EALDH1A1LMNAMAPTHTT | |
| SCHEMBL196046 | 0.55 | ESR1 (0.53) | KDM4EALDH1A1MAPTTP53HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0259206-B1 | DERIVATIVES OF 1,4-DIHYDROPYRIDINE, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ADIR ET COMPAGNIE (FR) | 1991-10-09 | — | — | EP | disclosed |
| EP-0259206-A1 | Derivatives of 1,4-dihydropyridine, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1988-03-09 | — | — | EP | disclosed |