Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.54 |
| ▸ | ELANE | P08246 | 2/20 | 0.53 |
| ▸ | CTSB | P07858 | 3/20 | 0.53 |
| ▸ | CTSV | O60911 | 1/20 | 0.53 |
| ▸ | CTSL | P07711 | 1/20 | 0.53 |
| ▸ | CTSS | P25774 | 1/20 | 0.53 |
| ▸ | BACE1 | P56817 | 1/20 | 0.53 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.51 |
| ▸ | MME | P08473 | 7/20 | 0.50 |
| ▸ | ACE | P12821 | 4/20 | 0.50 |
| ▸ | CPA1 | P15085 | 4/20 | 0.50 |
| ▸ | ACE2 | Q9BYF1 | 4/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9830982 | 1.00 | MEN1 (0.58) | MEN1KMT2AHRH4ELANECTSB | |
| SCHEMBL9716712 | 0.89 | ELANE (0.64) | MEN1KMT2AHRH4ELANECTSB | |
| SCHEMBL10658026 | 0.89 | ELANE (0.64) | MEN1KMT2AHRH4ELANECTSB | |
| SCHEMBL12518059 | 0.86 | BACE1 (0.61) | MEN1KMT2AELANECTSBCTSV | |
| SCHEMBL30291662 | 0.83 | CTSB (0.56) | MEN1KMT2AHRH4ELANECTSB | |
| SCHEMBL7648431 | 0.81 | ELANE (0.59) | MEN1KMT2AELANECTSBCTSV | |
| SCHEMBL9829713 | 0.81 | ACE (0.60) | CTSLCTSSMMEACECPA1 | |
| SCHEMBL9829719 | 0.81 | ACE (0.60) | CTSLCTSSMMEACECPA1 | |
| SCHEMBL7646585 | 0.81 | CTSB (0.58) | MEN1KMT2AELANECTSBCTSV | |
| SCHEMBL2405015 | 0.80 | PLK1 (0.60) | L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0226304-B1 | COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC | SANKYO COMPANY LIMITED (JP) | 1991-08-28 | — | — | EP | disclosed |
| US-4757066-A | Reduces renal toxicity | SANKYO COMPANY LIMITED (JP) | 1988-07-12 | — | — | US | disclosed |
| EP-0226304-A1 | Composition containing a penem or carbapenem antibiotic | SANKYO COMPANY LIMITED (JP) | 1987-06-24 | — | — | EP | disclosed |