Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 9/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | ZDHHC20 | Q5W0Z9 | 2/20 | 0.42 |
| ▸ | NAAA | Q02083 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28342234 | 0.88 | TSHR (0.72) | TSHRHPGDALDH1A1CYP3A4HCAR2 | |
| SCHEMBL28111622 | 0.88 | TSHR (0.72) | TSHRHPGDALDH1A1CYP3A4HCAR2 | |
| SCHEMBL27797563 | 0.86 | TSHR (0.75) | TSHRHPGDALDH1A1CYP3A4HCAR2 | |
| SCHEMBL4908448 | 0.85 | TSHR (0.56) | TSHRHPGDALDH1A1CYP3A4ATM | |
| SCHEMBL13898696 | 0.84 | TSHR (0.68) | TSHRHPGDALDH1A1CYP3A4HCAR2 | |
| Acrylonitrile SCHEMBL7618129 | 0.84 | TSHR (0.68) | TSHRHPGDALDH1A1CYP3A4HCAR2 | |
| Acrylonitrile SCHEMBL10712078 | 0.84 | TSHR (0.68) | TSHRHPGDALDH1A1CYP3A4HCAR2 | |
| Acrylonitrile SCHEMBL9872501 | 0.84 | TSHR (0.68) | TSHRHPGDALDH1A1CYP3A4HCAR2 | |
| Water SCHEMBL27806311 | 0.84 | TSHR (0.78) | TSHRHPGDALDH1A1CYP3A4HCAR2 | |
| SCHEMBL14967 | 0.84 | TSHR (0.84) | TSHRHPGDALDH1A1CYP3A4HCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0262255-B1 | ACRYLOXYMETHYL SUBSTITUTED FATTY COMPOUNDS | HENKEL CORPORATION (a Delaware corp.) (US) | 1991-08-28 | — | — | EP | disclosed |
| EP-0262255-A1 | Acryloxymethyl substituted fatty compounds | HENKEL CORPORATION (a Delaware corp.) (US) | 1988-04-06 | — | — | EP | disclosed |
| US-4626582-A | Acryloxymethyl substituted fatty compounds | HENKEL CORPORATION (US) | 1986-12-02 | — | — | US | disclosed |