Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 3/20 | 0.61 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | GPR88 | Q9GZN0 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | CRHBP | P24387 | 2/20 | 0.50 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | KDM4A | O75164 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9831283 | 1.00 | MME (0.61) | MMEKCNQ2MAPTGPR88POLB | |
| SCHEMBL9828894 | 0.91 | MME (0.63) | MMEKCNQ2MAPTGPR88POLB | |
| SCHEMBL9828899 | 0.91 | MME (0.63) | MMEKCNQ2MAPTGPR88POLB | |
| SCHEMBL1449796 | 0.90 | KCNQ2 (0.55) | MMEKCNQ2MAPTGPR88POLB | |
| SCHEMBL4066768 | 0.90 | MME (0.60) | MMEKCNQ2MAPTGPR88POLB | |
| SCHEMBL2330325 | 0.88 | MME (0.49) | MMEKCNQ2MAPTGPR88POLB | |
| SCHEMBL2330908 | 0.86 | LTA4H (0.54) | KCNQ2MAPTALDH1A1 | |
| SCHEMBL2330911 | 0.86 | LTA4H (0.54) | KCNQ2MAPTALDH1A1 | |
| SCHEMBL402068 | 0.86 | KMT2A (0.53) | MMEKCNQ2MAPTPOLBALDH1A1 | |
| SCHEMBL4268528 | 0.84 | MME (0.61) | MMEKCNQ2MAPTPOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0226304-B1 | COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC | SANKYO COMPANY LIMITED (JP) | 1991-08-28 | — | — | EP | disclosed |
| US-4757066-A | Reduces renal toxicity | SANKYO COMPANY LIMITED (JP) | 1988-07-12 | — | — | US | disclosed |
| EP-0226304-A1 | Composition containing a penem or carbapenem antibiotic | SANKYO COMPANY LIMITED (JP) | 1987-06-24 | — | — | EP | disclosed |