Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.70 |
| ▸ | LMNA | P02545 | 4/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | HTT | P42858 | 4/20 | 0.54 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9830646 | 0.89 | GAA (0.75) | POLBLMNAGAASMN1; SMN2RXFP1 | |
| SCHEMBL10475128 | 0.84 | GAA (0.59) | POLBLMNAGAAL3MBTL1TP53 | |
| SCHEMBL8373805 | 0.84 | POLB (1.00) | POLBLMNAGAAL3MBTL1TP53 | |
| SCHEMBL6450629 | 0.81 | GAA (0.64) | LMNAGAAL3MBTL1KDM4EALDH1A1 | |
| SCHEMBL6454315 | 0.81 | KAT6A (0.65) | LMNAGAAALDH1A1MEN1MAPT | |
| SCHEMBL28636438 | 0.81 | KDM4E (0.74) | POLBGAAKDM4EALDH1A1HTT | |
| SCHEMBL6449862 | 0.80 | GAA (0.62) | POLBLMNAGAAL3MBTL1KDM4E | |
| SCHEMBL15129266 | 0.79 | LMNA (0.70) | LMNAGAATP53KDM4ESMN1; SMN2 | |
| SCHEMBL3705046 | 0.78 | KDM4E (0.52) | POLBLMNAGAAL3MBTL1TP53 | |
| SCHEMBL16220966 | 0.77 | LMNA (0.54) | POLBLMNAGAAKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0185256-B1 | TRIAZOLE DERIVATES, THEIR PREPARATION AND THEIR USE AS PESTICIDES | CIBA-GEIGY AG (CH) | 1991-01-30 | — | — | EP | disclosed |
| US-4788210-A | PESTICIDES | HOFFMANN-LA ROCHE INC. (US) | 1988-11-29 | — | — | US | disclosed |
| EP-0185256-A2 | Triazole derivates, their preparation and their use as pesticides | CIBA-GEIGY AG (CH) | 1986-06-25 | — | — | EP | disclosed |