Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 4/20 | 0.54 |
| ▸ | CA1 | P00915 | 4/20 | 0.54 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.40 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.40 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.38 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.38 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | FDPS | P14324 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7325930 | 1.00 | CA2 (0.54) | CA2CA1EPHX1SLC15A1MAPK1 | |
| SCHEMBL7316786 | 1.00 | CA2 (0.54) | CA2CA1EPHX1SLC15A1MAPK1 | |
| SCHEMBL4023785 | 0.93 | CA1 (0.47) | CA2CA1EPHX1MAPK1SLC1A2 | |
| SCHEMBL31560160 | 0.91 | EPHX1 (0.48) | CA2CA1EPHX1MAPK1TP53 | |
| SCHEMBL16393900 | 0.91 | EPHX1 (0.48) | CA2CA1EPHX1MAPK1TP53 | |
| SCHEMBL21670103 | 0.91 | EPHX1 (0.48) | CA2CA1EPHX1MAPK1TP53 | |
| SCHEMBL6205731 | 0.86 | CA1 (0.41) | CA2CA1EPHX1SLC1A3SLC1A2 | |
| SCHEMBL1577891 | 0.86 | CA1 (0.41) | CA2CA1EPHX1SLC1A3SLC1A2 | |
| SCHEMBL6204488 | 0.86 | CA1 (0.41) | CA2CA1EPHX1SLC1A3SLC1A2 | |
| SCHEMBL2585299 | 0.84 | CA2 (0.52) | CA2CA1EPHX1SLC15A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0439556-A4 | HETEROCYCLIC PEPTIDE RENIN INHIBITORS | — | 1991-10-30 | — | — | EP | disclosed |