Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 16/20 | 0.51 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9828377 | 0.85 | HSD11B1 (0.52) | HSD11B1 | |
| SCHEMBL9828373 | 0.85 | HSD11B1 (0.52) | HSD11B1 | |
| SCHEMBL9829202 | 0.81 | HSD11B1 (0.48) | HSD11B1TRPA1TRPM8TRPV1ATM | |
| SCHEMBL9705543 | 0.80 | HSD11B1 (0.62) | HSD11B1TRPA1 | |
| SCHEMBL9829445 | 0.80 | HSD11B1 (0.52) | HSD11B1 | |
| SCHEMBL9829453 | 0.80 | HSD11B1 (0.52) | HSD11B1 | |
| SCHEMBL9830794 | 0.79 | HSD11B1 (0.53) | HSD11B1TRPA1TRPM8TRPV1P2RX7 | |
| SCHEMBL9830270 | 0.77 | HSD11B1 (0.51) | HSD11B1TRPA1TRPM8TRPV1P2RX7 | |
| SCHEMBL9830637 | 0.77 | HSD11B1 (0.54) | HSD11B1 | |
| SCHEMBL9828654 | 0.77 | HSD11B1 (0.54) | HSD11B1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0185256-B1 | TRIAZOLE DERIVATES, THEIR PREPARATION AND THEIR USE AS PESTICIDES | CIBA-GEIGY AG (CH) | 1991-01-30 | — | — | EP | disclosed |
| US-4788210-A | PESTICIDES | HOFFMANN-LA ROCHE INC. (US) | 1988-11-29 | — | — | US | disclosed |