Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SCN1A | P35498 | 1/20 | 0.32 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.32 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9831841 | 0.88 | TSHR (0.38) | TSHRUSP2ALDH1A1GAAKMT2A | |
| Flumetsulam SCHEMBL54906 | 0.87 | TSHR (0.40) | TSHRUSP2ALDH1A1GAAMAPK1 | |
| Flumetsulam SCHEMBL20723426 | 0.86 | TSHR (0.39) | TSHRUSP2ALDH1A1GAAMAPK1 | |
| Flumetsulam SCHEMBL20723449 | 0.86 | TSHR (0.39) | TSHRUSP2ALDH1A1GAAMAPK1 | |
| SCHEMBL10664258 | 0.86 | SMN1; SMN2 (0.37) | TSHRSCN1ASCN5ASCN8AALDH1A1 | |
| SCHEMBL9832538 | 0.84 | TSHR (0.38) | TSHRUSP2ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL9830484 | 0.83 | TSHR (0.58) | TSHRUSP2ALDH1A1 | |
| SCHEMBL9832174 | 0.83 | GRM5 (0.35) | TSHRSCN1ASCN5ASCN8AP2RX7 | |
| Flumetsulam SCHEMBL22587375 | 0.82 | TSHR (0.37) | TSHRUSP2ALDH1A1GAAMAPK1 | |
| SCHEMBL9832548 | 0.82 | HTR6 (0.39) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0142152-B1 | Novel substituted 1,2,4-triazolo- [1,5-a] pyrimidine-2-sulfonamides and compositions and methods of controlling undesired vegetation and suppressing the nitrification of ammonium nitrogen in soil | THE DOW CHEMICAL COMPANY (US) | 1991-03-20 | — | — | EP | claimed |
| US-4755212-A | Novel substituted 1,2,4-triazolo[1,5-a]pyrimidine-2-sulfonamides and compositions and method for inhibiting pollen formation in corn | THE DOW CHEMICAL COMPANY (US) | 1988-07-05 | — | — | US | disclosed |
| US-4741764-A | SUPPRESSION OF NITRIFICATION OF AMMONIUM NITROGEN IN THE SOIL | THE DOW CHEMICAL COMPANY (US) | 1988-05-03 | — | — | US | disclosed |
| US-4740233-A | Substituted 1,2,4-triazolo[1,5-a]-pyrimidine-2-sulfonamides and compositions and methods of controlling undesired vegetation and suppressing the nitrification of ammonium nitrogen in soil | THE DOW CHEMICAL COMPANY (US) | 1988-04-26 | — | — | US | disclosed |