SCHEMBL9832026

SCHEMBL9832026

CC(C)(C)OC(=O)NC(CC1CCCCC1)C(O)C(OCc1ccccc1)C(=O)O

nearest known ligand 0.55

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
REN P00797 17/20 0.55
CTSD P07339 1/20 0.46
CTSE P14091 1/20 0.46
CTSL P07711 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9831700 0.92 REN (0.54) RENCTSDCTSECTSL
SCHEMBL9832827 0.92 REN (0.54) RENCTSDCTSECTSL
SCHEMBL9518203 0.88 REN (0.51) RENCTSDCTSECTSL
SCHEMBL9518196 0.88 REN (0.51) RENCTSDCTSECTSL
SCHEMBL10774796 0.87 REN (0.50) RENCTSL
SCHEMBL10774805 0.87 REN (0.50) RENCTSL
SCHEMBL10774812 0.87 REN (0.50) RENCTSL
SCHEMBL9514515 0.86 REN (0.51) RENCTSDCTSE
SCHEMBL9515771 0.86 REN (0.49) RENCTSDCTSECTSL
SCHEMBL9514521 0.86 REN (0.51) RENCTSDCTSE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0258289-A4 PEPTIDE ANALOGS 1991-01-02 EP disclosed
US-4826958-A HYPOTENSIVE AGENTS ABBOTT LABORATORIES (US) 1989-05-02 US disclosed
EP-0258289-A1 PEPTIDE ANALOGS ABBOTT LABORATORIES (US) 1988-03-09 EP disclosed
WO-1987004349-A1 PEPTIDE ANALOGS DELLARIA JOSEPH 1987-07-30 WO disclosed
EP-0184855-A2 Resin inhibiting compounds ABBOTT LABORATORIES (US) 1986-06-18 EP disclosed