Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | CNR2 | P34972 | 6/20 | 0.51 |
| ▸ | MME | P08473 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.49 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9832132 | 1.00 | POLB (0.52) | POLBALDH1A1CNR2MMEMEN1 | |
| SCHEMBL4412844 | 0.89 | POLB (0.59) | POLBALDH1A1CNR2MEN1CYP1A2 | |
| SCHEMBL4412847 | 0.89 | POLB (0.59) | POLBALDH1A1CNR2MEN1CYP1A2 | |
| SCHEMBL10432164 | 0.89 | POLB (0.59) | POLBALDH1A1CNR2MEN1CYP1A2 | |
| SCHEMBL6428188 | 0.89 | POLB (0.50) | POLBALDH1A1CNR2MEN1CYP1A2 | |
| SCHEMBL5967124 | 0.87 | MEN1 (0.51) | POLBALDH1A1CNR2MEN1CYP1A2 | |
| SCHEMBL27528032 | 0.87 | MEN1 (0.51) | POLBALDH1A1CNR2MEN1CYP1A2 | |
| Alanine SCHEMBL1679645 | 0.84 | POLB (0.54) | POLBALDH1A1CNR2MEN1CYP1A2 | |
| SCHEMBL15387515 | 0.83 | MME (0.55) | POLBALDH1A1CNR2MMEMEN1 | |
| SCHEMBL15387514 | 0.83 | MME (0.55) | POLBALDH1A1CNR2MMEMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0226304-B1 | COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC | SANKYO COMPANY LIMITED (JP) | 1991-08-28 | — | — | EP | disclosed |
| US-4757066-A | Reduces renal toxicity | SANKYO COMPANY LIMITED (JP) | 1988-07-12 | — | — | US | disclosed |
| EP-0226304-A1 | Composition containing a penem or carbapenem antibiotic | SANKYO COMPANY LIMITED (JP) | 1987-06-24 | — | — | EP | disclosed |