Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 5/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | MITF | O75030 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | XBP1 | P17861 | 1/20 | 0.36 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.36 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4964578 | 0.87 | — | — | |
| SCHEMBL10189844 | 0.85 | — | — | |
| SCHEMBL8139560 | 0.81 | ALDH1A1 (0.37) | ALDH1A1SMN1; SMN2TSHRHTTMAPT | |
| SCHEMBL726450 | 0.79 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2HTTMAPTKDM4E | |
| SCHEMBL1067952 | 0.79 | CYP1A2 (0.39) | ALDH1A1SMN1; SMN2HTTMAPTKDM4E | |
| SCHEMBL1935273 | 0.77 | ALDH1A1 (0.39) | ALDH1A1SMN1; SMN2TSHRHTTMAPT | |
| SCHEMBL6774860 | 0.77 | ALDH1A1 (0.39) | ALDH1A1SMN1; SMN2HTTMAPTKDM4E | |
| SCHEMBL14067639 | 0.75 | ALDH1A1 (0.33) | ALDH1A1SMN1; SMN2HTTMAPTKDM4E | |
| SCHEMBL9736805 | 0.74 | — | — | |
| SCHEMBL3966474 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0217256-B1 | METHOD FOR QUENCHING FLUORESCENCE, AND CATIONIC DERIVATIVES OF NAPHTHALENE-PERI-DICARBOXAMIDE | BAYER AG (DE) | 1991-03-06 | — | — | EP | disclosed |
| US-4919848-A | Process for the quenching of fluorescence, and new cationic naphthalene-peri-dicarboxylic acid imide derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1990-04-24 | — | — | US | disclosed |
| EP-0217256-A2 | Method for quenching fluorescence, and cationic derivatives of naphthalene-peri-dicarboxamide | BAYER AG (DE) | 1987-04-08 | — | — | EP | disclosed |
| US-4128538-A | Crosslinking polymeric dye mordant composition reaction product of bisalkane or bisarene sulfonate and vinyl polymer | EASTMAN KODAK COMPANY (US) | 1978-12-05 | — | — | US | disclosed |