Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 6/20 | 0.64 |
| ▸ | TERT | O14746 | 3/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.52 |
| ▸ | PPARG | P37231 | 3/20 | 0.52 |
| ▸ | PPARD | Q03181 | 3/20 | 0.52 |
| ▸ | PPARA | Q07869 | 3/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | BLM | P54132 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | FABP4 | P15090 | 2/20 | 0.52 |
| ▸ | FAAH | O00519 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | TOP1 | P11387 | 2/20 | 0.52 |
| ▸ | GMNN | O75496 | 1/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9832172 | 1.00 | EPHX2 (0.64) | EPHX2TERTPTPN1PPARGPPARD | |
| SCHEMBL12512134 | 0.89 | EPHX2 (0.51) | EPHX2PPARGPPARDPPARACYP1A2 | |
| SCHEMBL16658679 | 0.88 | DNM1 (0.50) | EPHX2PPARGPPARDPPARATDP1 | |
| SCHEMBL6949703 | 0.88 | DNM1 (0.50) | EPHX2PPARGPPARDPPARATDP1 | |
| SCHEMBL4601205 | 0.88 | DNM1 (0.50) | EPHX2PPARGPPARDPPARATDP1 | |
| SCHEMBL3440790 | 0.88 | DNM1 (0.50) | EPHX2PPARGPPARDPPARATDP1 | |
| SCHEMBL1902069 | 0.88 | DNM1 (0.50) | EPHX2PPARGPPARDPPARATDP1 | |
| SCHEMBL2180094 | 0.88 | DNM1 (0.50) | EPHX2PPARGPPARDPPARATDP1 | |
| SCHEMBL16658678 | 0.88 | DNM1 (0.50) | EPHX2PPARGPPARDPPARATDP1 | |
| SCHEMBL18660081 | 0.88 | DNM1 (0.50) | EPHX2PPARGPPARDPPARATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0262255-B1 | ACRYLOXYMETHYL SUBSTITUTED FATTY COMPOUNDS | HENKEL CORPORATION (a Delaware corp.) (US) | 1991-08-28 | — | — | EP | disclosed |
| EP-0262255-A1 | Acryloxymethyl substituted fatty compounds | HENKEL CORPORATION (a Delaware corp.) (US) | 1988-04-06 | — | — | EP | disclosed |
| US-4626582-A | Acryloxymethyl substituted fatty compounds | HENKEL CORPORATION (US) | 1986-12-02 | — | — | US | disclosed |