Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 4/20 | 0.41 |
| ▸ | PPARG | P37231 | 5/20 | 0.41 |
| ▸ | AKT1 | P31749 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | FLT3 | P36888 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9831240 | 0.85 | FFAR1 (0.41) | FFAR1PPARGAKT1PIK3CAALDH1A1 | |
| SCHEMBL9830775 | 0.83 | PPARG (0.43) | FFAR1PPARGAKT1PIK3CAALDH1A1 | |
| SCHEMBL377496 | 0.81 | FFAR1 (0.43) | FFAR1PPARGAKT1PIK3CAALDH1A1 | |
| SCHEMBL9558560 | 0.80 | PPARG (0.49) | FFAR1PPARGAKT1PIK3CAALDH1A1 | |
| SCHEMBL9831735 | 0.80 | PPARG (0.44) | FFAR1PPARGAKT1PIK3CAALDH1A1 | |
| SCHEMBL9832774 | 0.80 | ALDH1A1 (0.45) | FFAR1PPARGAKT1PIK3CAALDH1A1 | |
| SCHEMBL9565667 | 0.79 | MAPT (0.53) | FFAR1PPARGAKT1PIK3CAALDH1A1 | |
| SCHEMBL9831543 | 0.79 | MAPT (0.58) | FFAR1PPARGAKT1PIK3CAALDH1A1 | |
| SCHEMBL9832866 | 0.78 | FFAR1 (0.57) | FFAR1PPARGPPARA | |
| SCHEMBL9829846 | 0.76 | PPARG (0.49) | FFAR1PPARGALDH1A1NPSR1PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0283035-B1 | BENZOXAZOLE DERIVATIVES AND PREPARATION THEREOF | TANABE SEIYAKU CO., LTD. (JP) | 1991-11-06 | — | — | EP | disclosed |
| US-4948900-A | INTERMEDIATES FOR DIABETES THERAPEUTIC AGENTS | TANABE SEIYAKU CO., LTD. (JP) | 1990-08-14 | — | — | US | disclosed |
| US-4897393-A | ANTIDIABETIC AGENTS | TANABE SEIYAKU CO., LTD. (JP) | 1990-01-30 | — | — | US | disclosed |
| EP-0283035-A1 | Benzoxazole derivatives and preparation thereof | TANABE SEIYAKU CO., LTD. (JP) | 1988-09-21 | — | — | EP | disclosed |