Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9831463 | 0.90 | TSHR (0.56) | TSHRALDH1A1USP2LMNAPOLB | |
| SCHEMBL9831981 | 0.88 | ALDH1A1 (0.52) | TSHRALDH1A1USP2LMNAPOLB | |
| SCHEMBL9833388 | 0.87 | TSHR (0.50) | TSHRALDH1A1USP2LMNAPOLB | |
| SCHEMBL9834165 | 0.87 | DHODH (0.41) | TSHRALDH1A1POLBSMN1; SMN2MEN1 | |
| SCHEMBL9832614 | 0.87 | TSHR (0.55) | TSHRALDH1A1USP2LMNAPOLB | |
| SCHEMBL9832602 | 0.87 | TSHR (0.57) | TSHRALDH1A1USP2LMNAPOLB | |
| SCHEMBL9834364 | 0.87 | TSHR (0.57) | TSHRALDH1A1USP2LMNAPOLB | |
| SCHEMBL9832297 | 0.86 | TSHR (0.56) | TSHRALDH1A1USP2LMNAPOLB | |
| SCHEMBL9832329 | 0.85 | TSHR (0.55) | TSHRALDH1A1USP2LMNAPOLB | |
| SCHEMBL8351725 | 0.83 | TSHR (0.64) | TSHRALDH1A1USP2LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0142152-B1 | Novel substituted 1,2,4-triazolo- [1,5-a] pyrimidine-2-sulfonamides and compositions and methods of controlling undesired vegetation and suppressing the nitrification of ammonium nitrogen in soil | THE DOW CHEMICAL COMPANY (US) | 1991-03-20 | — | — | EP | claimed |