Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9830997 | 0.91 | TSHR (0.54) | ALDH1A1GAAHSD17B10TSHRMEN1 | |
| SCHEMBL9830376 | 0.89 | ALDH1A1 (0.51) | ALDH1A1GAAHSD17B10TSHRMEN1 | |
| SCHEMBL10664447 | 0.88 | HPGD (0.43) | ALDH1A1GAAHSD17B10TSHRMEN1 | |
| SCHEMBL9831713 | 0.88 | TSHR (0.48) | ALDH1A1GAAHSD17B10TSHRMEN1 | |
| SCHEMBL9831418 | 0.87 | ALDH1A1 (0.56) | ALDH1A1GAAHSD17B10TSHRMEN1 | |
| SCHEMBL9832683 | 0.87 | ALDH1A1 (0.50) | ALDH1A1GAATSHRKMT2AKDM4E | |
| SCHEMBL9831537 | 0.87 | TSHR (0.52) | ALDH1A1GAAHSD17B10TSHRMEN1 | |
| SCHEMBL9831934 | 0.87 | TSHR (0.51) | ALDH1A1TSHRMEN1GLAKMT2A | |
| SCHEMBL9832454 | 0.84 | ALDH1A1 (0.49) | ALDH1A1GAAHSD17B10TSHRMEN1 | |
| SCHEMBL9832394 | 0.84 | ALDH1A1 (0.49) | ALDH1A1GAAHSD17B10TSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0142152-B1 | Novel substituted 1,2,4-triazolo- [1,5-a] pyrimidine-2-sulfonamides and compositions and methods of controlling undesired vegetation and suppressing the nitrification of ammonium nitrogen in soil | THE DOW CHEMICAL COMPANY (US) | 1991-03-20 | — | — | EP | claimed |