Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 11/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9833313 | 0.85 | REN (0.41) | RENCA1CA2CA7HDAC4 | |
| SCHEMBL9079107 | 0.82 | HDAC4 (0.42) | RENCA1CA2CA7HDAC4 | |
| SCHEMBL9079109 | 0.82 | HDAC4 (0.42) | RENCA1CA2CA7HDAC4 | |
| SCHEMBL7354951 | 0.82 | HDAC4 (0.42) | RENCA1CA2CA7HDAC4 | |
| SCHEMBL7354944 | 0.82 | HDAC4 (0.42) | RENCA1CA2CA7HDAC4 | |
| SCHEMBL9833654 | 0.78 | REN (0.42) | RENHDAC4HDAC1HDAC6 | |
| SCHEMBL10606974 | 0.78 | REN (0.37) | RENCA1CA2 | |
| SCHEMBL9746179 | 0.74 | HDAC4 (0.40) | RENCA1CA2CA7HDAC4 | |
| SCHEMBL7438948 | 0.74 | CA1 (0.45) | RENCA1CA2CA7 | |
| SCHEMBL10337105 | 0.74 | HDAC4 (0.40) | RENCA1CA2CA7HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0258289-A4 | PEPTIDE ANALOGS | — | 1991-01-02 | — | — | EP | disclosed |
| US-4857507-A | HYPOTENSIVE AGENT | ABBOTT LABORATORIES (US) | 1989-08-15 | — | — | US | disclosed |
| EP-0258289-A1 | PEPTIDE ANALOGS | ABBOTT LABORATORIES (US) | 1988-03-09 | — | — | EP | disclosed |
| WO-1987004349-A1 | PEPTIDE ANALOGS | DELLARIA JOSEPH | 1987-07-30 | — | — | WO | disclosed |